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A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites.
Birnbaum J, Scharf S, Schmidt S, Jonscher E, Hoeijmakers WAM, Flemming S, Toenhake CG, Schmitt M, Sabitzki R, Bergmann B, Fröhlke U, Mesén-Ramírez P, Blancke Soares A, Herrmann H, Bártfai R, Spielmann T. Birnbaum J, et al. Among authors: flemming s. Science. 2020 Jan 3;367(6473):51-59. doi: 10.1126/science.aax4735. Science. 2020. PMID: 31896710
Uncovering common principles in protein export of malaria parasites.
Grüring C, Heiber A, Kruse F, Flemming S, Franci G, Colombo SF, Fasana E, Schoeler H, Borgese N, Stunnenberg HG, Przyborski JM, Gilberger TW, Spielmann T. Grüring C, et al. Among authors: flemming s. Cell Host Microbe. 2012 Nov 15;12(5):717-29. doi: 10.1016/j.chom.2012.09.010. Cell Host Microbe. 2012. PMID: 23159060 Free article.
Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in Plasmodium falciparum protein export.
Heiber A, Kruse F, Pick C, Grüring C, Flemming S, Oberli A, Schoeler H, Retzlaff S, Mesén-Ramírez P, Hiss JA, Kadekoppala M, Hecht L, Holder AA, Gilberger TW, Spielmann T. Heiber A, et al. Among authors: flemming s. PLoS Pathog. 2013;9(8):e1003546. doi: 10.1371/journal.ppat.1003546. Epub 2013 Aug 8. PLoS Pathog. 2013. PMID: 23950716 Free PMC article.
Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding.
Boddey JA, O'Neill MT, Lopaticki S, Carvalho TG, Hodder AN, Nebl T, Wawra S, van West P, Ebrahimzadeh Z, Richard D, Flemming S, Spielmann T, Przyborski J, Babon JJ, Cowman AF. Boddey JA, et al. Among authors: flemming s. Nat Commun. 2016 Feb 1;7:10470. doi: 10.1038/ncomms10470. Nat Commun. 2016. PMID: 26832821 Free PMC article.
A genetic system to study Plasmodium falciparum protein function.
Birnbaum J, Flemming S, Reichard N, Soares AB, Mesén-Ramírez P, Jonscher E, Bergmann B, Spielmann T. Birnbaum J, et al. Among authors: flemming s. Nat Methods. 2017 Apr;14(4):450-456. doi: 10.1038/nmeth.4223. Epub 2017 Mar 13. Nat Methods. 2017. PMID: 28288121
PfVPS45 Is Required for Host Cell Cytosol Uptake by Malaria Blood Stage Parasites.
Jonscher E, Flemming S, Schmitt M, Sabitzki R, Reichard N, Birnbaum J, Bergmann B, Höhn K, Spielmann T. Jonscher E, et al. Among authors: flemming s. Cell Host Microbe. 2019 Jan 9;25(1):166-173.e5. doi: 10.1016/j.chom.2018.11.010. Epub 2018 Dec 20. Cell Host Microbe. 2019. PMID: 30581113 Free article.
How cortical waves drive fission of motile cells.
Flemming S, Font F, Alonso S, Beta C. Flemming S, et al. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6330-6338. doi: 10.1073/pnas.1912428117. Epub 2020 Mar 11. Proc Natl Acad Sci U S A. 2020. PMID: 32161132 Free PMC article.
122 results