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Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Li X, Wu F, Günther S, Looso M, Kuenne C, Zhang T, Wiesnet M, Klatt S, Zukunft S, Fleming I, Poschet G, Wietelmann A, Atzberger A, Potente M, Yuan X, Braun T. Li X, et al. Among authors: fleming i. Nature. 2023 Oct;622(7983):619-626. doi: 10.1038/s41586-023-06585-5. Epub 2023 Sep 27. Nature. 2023. PMID: 37758950 Free PMC article.
Impaired Detoxification of Trans, Trans-2,4-Decadienal, an Oxidation Product from Omega-6 Fatty Acids, Alters Insulin Signaling, Gluconeogenesis and Promotes Microvascular Disease.
Qian X, Klatt S, Bennewitz K, Wohlfart DP, Lou B, Meng Y, Buettner M, Poschet G, Morgenstern J, Fleming T, Sticht C, Hausser I, Fleming I, Szendroedi J, Nawroth PP, Kroll J. Qian X, et al. Among authors: fleming i. Adv Sci (Weinh). 2024 Jan;11(4):e2302325. doi: 10.1002/advs.202302325. Epub 2023 Dec 7. Adv Sci (Weinh). 2024. PMID: 38059818 Free PMC article.
Hemojuvelin mediated hepcidin induction requires both bone morphogenetic protein type I receptors ALK2 and ALK3.
Dogan DY, Urzica EI, Hornung I, Kastl P, Oguama D, Fette FM, Nguyen LH, Rosenbauer F, Zacharowski K, Klingmüller U, Gradhand E, von Knethen A, Popp R, Fleming I, Schrader L, Steinbicker AU. Dogan DY, et al. Among authors: fleming i. Blood Adv. 2024 Apr 8:bloodadvances.2023012322. doi: 10.1182/bloodadvances.2023012322. Online ahead of print. Blood Adv. 2024. PMID: 38588481
Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis.
Tamiato A, Tombor LS, Fischer A, Muhly-Reinholz M, Vanicek LR, Toğru BN, Neitz J, Glaser SF, Merten M, Rodriguez Morales D, Kwon J, Klatt S, Schumacher B, Günther S, Abplanalp WT, John D, Fleming I, Wettschureck N, Dimmeler S, Luxán G. Tamiato A, et al. Among authors: fleming i. Circ Res. 2024 Apr 2. doi: 10.1161/CIRCRESAHA.123.324183. Online ahead of print. Circ Res. 2024. PMID: 38563133 Free article.
615 results