Flavell SU - Search Results

1

The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-cell Leukaemia.

Flavell DJ, Holmes SE, Warnes SL, Flavell SU. Flavell DJ, et al. Among authors: flavell su. Biomedicines. 2019 Feb 16;7(1):13. doi: 10.3390/biomedicines7010013. Biomedicines. 2019. PMID: 30781517 Free PMC article.

2

The Effect of Small Molecule Pharmacological Agents on the Triterpenoid Saponin Induced Endolysosomal Escape of Saporin and a Saporin-Based Immunotoxin in Target Human Lymphoma Cells.

Wensley HJ, Smith WS, Holmes SE, Flavell SU, Flavell DJ. Wensley HJ, et al. Among authors: flavell su. Biomedicines. 2021 Mar 15;9(3):300. doi: 10.3390/biomedicines9030300. Biomedicines. 2021. PMID: 33804080 Free PMC article.

3

The anti-CD20 antibody rituximab augments the immunospecific therapeutic effectiveness of an anti-CD19 immunotoxin directed against human B-cell lymphoma.

Flavell DJ, Warnes SL, Bryson CJ, Field SA, Noss AL, Packham G, Flavell SU. Flavell DJ, et al. Among authors: flavell su. Br J Haematol. 2006 Jul;134(2):157-70. doi: 10.1111/j.1365-2141.2006.06155.x. Epub 2006 Jun 12. Br J Haematol. 2006. PMID: 16771848 Free article.

4

Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukaemia and lymphoma cells is partially immunospecific and target molecule dependent.

Holmes SE, Bachran C, Fuchs H, Weng A, Melzig MF, Flavell SU, Flavell DJ. Holmes SE, et al. Among authors: flavell su. Immunopharmacol Immunotoxicol. 2015 Feb;37(1):42-55. doi: 10.3109/08923973.2014.971964. Epub 2014 Oct 27. Immunopharmacol Immunotoxicol. 2015. PMID: 25347443

5

Membrane cholesterol is essential for triterpenoid saponin augmentation of a saporin-based immunotoxin directed against CD19 on human lymphoma cells.

Smith WS, Baker EJ, Holmes SE, Koster G, Hunt AN, Johnston DA, Flavell SU, Flavell DJ. Smith WS, et al. Among authors: flavell su. Biochim Biophys Acta Biomembr. 2017 May;1859(5):993-1007. doi: 10.1016/j.bbamem.2017.02.013. Epub 2017 Feb 21. Biochim Biophys Acta Biomembr. 2017. PMID: 28235471 Free article.

6

Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents.

Smith WS, Johnston DA, Holmes SE, Wensley HJ, Flavell SU, Flavell DJ. Smith WS, et al. Among authors: flavell su. Toxins (Basel). 2019 Feb 20;11(2):127. doi: 10.3390/toxins11020127. Toxins (Basel). 2019. PMID: 30791598 Free PMC article.

7

A Flow Cytometric Method to Quantify the Endosomal Escape of a Protein Toxin to the Cytosol of Target Cells.

Wensley HJ, Johnston DA, Smith WS, Holmes SE, Flavell SU, Flavell DJ. Wensley HJ, et al. Among authors: flavell su. Pharm Res. 2019 Dec 23;37(1):16. doi: 10.1007/s11095-019-2725-1. Pharm Res. 2019. PMID: 31873810 Free PMC article.

8

The Role of Cholesterol on Triterpenoid Saponin-Induced Endolysosomal Escape of a Saporin-Based Immunotoxin.

Smith WS, Johnston DA, Wensley HJ, Holmes SE, Flavell SU, Flavell DJ. Smith WS, et al. Among authors: flavell su. Int J Mol Sci. 2020 Nov 19;21(22):8734. doi: 10.3390/ijms21228734. Int J Mol Sci. 2020. PMID: 33228031 Free PMC article.

9

Effectiveness of combinations of bispecific antibodies for delivering saporin to human acute T-cell lymphoblastic leukaemia cell lines via CD7 and CD38 as cellular target molecules.

Flavell DJ, Cooper S, Morland B, French R, Flavell SU. Flavell DJ, et al. Among authors: flavell su. Br J Cancer. 1992 Apr;65(4):545-51. doi: 10.1038/bjc.1992.112. Br J Cancer. 1992. PMID: 1373293 Free PMC article.

10

Characteristics and performance of a bispecific F (ab'gamma)2 antibody for delivering saporin to a CD7+ human acute T-cell leukaemia cell line.

Flavell DJ, Cooper S, Morland B, Flavell SU. Flavell DJ, et al. Among authors: flavell su. Br J Cancer. 1991 Aug;64(2):274-80. doi: 10.1038/bjc.1991.291. Br J Cancer. 1991. PMID: 1716453 Free PMC article.

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