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HIV-1 Vpu restricts Fc-mediated effector functions in vivo.
Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, Flavell RA, Kirchhoff F, Hahn BH, Smith AB 3rd, Pazgier M, Nussenzweig MC, Kumar P, Finzi A. Prévost J, et al. Among authors: flavell ra. Cell Rep. 2022 Nov 8;41(6):111624. doi: 10.1016/j.celrep.2022.111624. Cell Rep. 2022. PMID: 36351384 Free PMC article.
Gene trajectory inference for single-cell data by optimal transport metrics.
Qu R, Cheng X, Sefik E, Stanley Iii JS, Landa B, Strino F, Platt S, Garritano J, Odell ID, Coifman R, Flavell RA, Myung P, Kluger Y. Qu R, et al. Among authors: flavell ra. Nat Biotechnol. 2024 Apr 5. doi: 10.1038/s41587-024-02186-3. Online ahead of print. Nat Biotechnol. 2024. PMID: 38580861
IL-10 constrains sphingolipid metabolism to limit inflammation.
York AG, Skadow MH, Oh J, Qu R, Zhou QD, Hsieh WY, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Smale ST, Crawford JM, Bensinger SJ, Flavell RA. York AG, et al. Among authors: flavell ra. Nature. 2024 Mar;627(8004):628-635. doi: 10.1038/s41586-024-07098-5. Epub 2024 Feb 21. Nature. 2024. PMID: 38383790 Free PMC article.
IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction.
Shiri AM, Zhang T, Bedke T, Zazara DE, Zhao L, Lücke J, Sabihi M, Fazio A, Zhang S, Tauriello DVF, Batlle E, Steglich B, Kempski J, Agalioti T, Nawrocki M, Xu Y, Riecken K, Liebold I, Brockmann L, Konczalla L, Bosurgi L, Mercanoglu B, Seeger P, Küsters N, Lykoudis PM, Heumann A, Arck PC, Fehse B, Busch P, Grotelüschen R, Mann O, Izbicki JR, Hackert T, Flavell RA, Gagliani N, Giannou AD, Huber S. Shiri AM, et al. Among authors: flavell ra. J Hepatol. 2024 Apr;80(4):634-644. doi: 10.1016/j.jhep.2023.12.015. Epub 2023 Dec 30. J Hepatol. 2024. PMID: 38160941 Free PMC article.
Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection.
Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, Gomez de Agüero M, Gagliani N, Flavell RA, Backes S, Kastenmüller W, Gasteiger G. Torcellan T, et al. Among authors: flavell ra. Immunity. 2024 Jan 9;57(1):124-140.e7. doi: 10.1016/j.immuni.2023.11.018. Epub 2023 Dec 28. Immunity. 2024. PMID: 38157853 Free PMC article.
1,209 results