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Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs.
Flavahan WA, Drier Y, Johnstone SE, Hemming ML, Tarjan DR, Hegazi E, Shareef SJ, Javed NM, Raut CP, Eschle BK, Gokhale PC, Hornick JL, Sicinska ET, Demetri GD, Bernstein BE. Flavahan WA, et al. Nature. 2019 Nov;575(7781):229-233. doi: 10.1038/s41586-019-1668-3. Epub 2019 Oct 16. Nature. 2019. PMID: 31666694 Free PMC article.
Insulator dysfunction and oncogene activation in IDH mutant gliomas.
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE. Flavahan WA, et al. Nature. 2016 Jan 7;529(7584):110-4. doi: 10.1038/nature16490. Epub 2015 Dec 23. Nature. 2016. PMID: 26700815 Free PMC article.
Epigenetic plasticity and the hallmarks of cancer.
Flavahan WA, Gaskell E, Bernstein BE. Flavahan WA, et al. Science. 2017 Jul 21;357(6348):eaal2380. doi: 10.1126/science.aal2380. Science. 2017. PMID: 28729483 Free PMC article. Review.
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suvà ML, Patel AP, Bernstein BE. Liau BB, et al. Among authors: flavahan wa. Cell Stem Cell. 2017 Feb 2;20(2):233-246.e7. doi: 10.1016/j.stem.2016.11.003. Epub 2016 Dec 15. Cell Stem Cell. 2017. PMID: 27989769 Free PMC article.
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN. Miller TE, et al. Among authors: flavahan wa. Nature. 2017 Jul 20;547(7663):355-359. doi: 10.1038/nature23000. Epub 2017 Jul 5. Nature. 2017. PMID: 28678782 Free PMC article.
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma.
Wang X, Yang K, Xie Q, Wu Q, Mack SC, Shi Y, Kim LJY, Prager BC, Flavahan WA, Liu X, Singer M, Hubert CG, Miller TE, Zhou W, Huang Z, Fang X, Regev A, Suvà ML, Hwang TH, Locasale JW, Bao S, Rich JN. Wang X, et al. Among authors: flavahan wa. Nat Neurosci. 2017 May;20(5):661-673. doi: 10.1038/nn.4537. Epub 2017 Mar 27. Nat Neurosci. 2017. PMID: 28346452 Free PMC article.
The tailless root of glioma: cancer stem cells.
Xie Q, Flavahan WA, Bao S, Rich J. Xie Q, et al. Among authors: flavahan wa. Cell Stem Cell. 2014 Aug 7;15(2):114-6. doi: 10.1016/j.stem.2014.07.004. Cell Stem Cell. 2014. PMID: 25105574 Free PMC article.
28 results