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The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Solis O, Beccari AR, Iaconis D, Talarico C, Ruiz-Bedoya CA, Nwachukwu JC, Cimini A, Castelli V, Bertini R, Montopoli M, Cocetta V, Borocci S, Prandi IG, Flavahan K, Bahr M, Napiorkowski A, Chillemi G, Ooka M, Yang X, Zhang S, Xia M, Zheng W, Bonaventura J, Pomper MG, Hooper JE, Morales M, Rosenberg AZ, Nettles KW, Jain SK, Allegretti M, Michaelides M. Solis O, et al. Among authors: flavahan k. Sci Adv. 2022 Dec 2;8(48):eadd4150. doi: 10.1126/sciadv.add4150. Epub 2022 Nov 30. Sci Adv. 2022. PMID: 36449624 Free PMC article.
Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model.
Dhakal S, Ruiz-Bedoya CA, Zhou R, Creisher PS, Villano JS, Littlefield K, Ruelas Castillo J, Marinho P, Jedlicka AE, Ordonez AA, Bahr M, Majewska N, Betenbaugh MJ, Flavahan K, Mueller ARL, Looney MM, Quijada D, Mota F, Beck SE, Brockhurst J, Braxton AM, Castell N, Stover M, D'Alessio FR, Metcalf Pate KA, Karakousis PC, Mankowski JL, Pekosz A, Jain SK, Klein SL; Johns Hopkins COVID-19 Hamster Study Group. Dhakal S, et al. Among authors: flavahan k. mBio. 2021 Aug 31;12(4):e0097421. doi: 10.1128/mBio.00974-21. Epub 2021 Jul 13. mBio. 2021. PMID: 34253053 Free PMC article.
124I-Iodo-DPA-713 Positron Emission Tomography in a Hamster Model of SARS-CoV-2 Infection.
Ruiz-Bedoya CA, Mota F, Ordonez AA, Foss CA, Singh AK, Praharaj M, Mahmud FJ, Ghayoor A, Flavahan K, De Jesus P, Bahr M, Dhakal S, Zhou R, Solis CV, Mulka KR, Bishai WR, Pekosz A, Mankowski JL, Villano J, Klein SL, Jain SK. Ruiz-Bedoya CA, et al. Among authors: flavahan k. Mol Imaging Biol. 2022 Feb;24(1):135-143. doi: 10.1007/s11307-021-01638-5. Epub 2021 Aug 23. Mol Imaging Biol. 2022. PMID: 34424479 Free PMC article.
Progression and Resolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Golden Syrian Hamsters.
Mulka KR, Beck SE, Solis CV, Johanson AL, Queen SE, McCarron ME, Richardson MR, Zhou R, Marinho P, Jedlicka A, Guerrero-Martin S, Shirk EN, Braxton AM, Brockhurst J, Creisher PS, Dhakal S, Brayton CF, Veenhuis RT, Metcalf Pate KA, Karakousis PC, Zahnow CA, Klein SL, Jain SK, Tarwater PM, Pekosz AS, Villano JS, Mankowski JL; Johns Hopkins COVID-19 Hamster Study Group. Mulka KR, et al. Am J Pathol. 2022 Feb;192(2):195-207. doi: 10.1016/j.ajpath.2021.10.009. Epub 2021 Nov 10. Am J Pathol. 2022. PMID: 34767812 Free PMC article.
Dynamic PET-facilitated modeling and high-dose rifampin regimens for Staphylococcus aureus orthopedic implant-associated infections.
Gordon O, Lee DE, Liu B, Langevin B, Ordonez AA, Dikeman DA, Shafiq B, Thompson JM, Sponseller PD, Flavahan K, Lodge MA, Rowe SP, Dannals RF, Ruiz-Bedoya CA, Read TD, Peloquin CA, Archer NK, Miller LS, Davis KM, Gobburu JVS, Jain SK. Gordon O, et al. Among authors: flavahan k. Sci Transl Med. 2021 Dec;13(622):eabl6851. doi: 10.1126/scitranslmed.abl6851. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851697 Free PMC article.
High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis.
Ruiz-Bedoya CA, Mota F, Tucker EW, Mahmud FJ, Reyes-Mantilla MI, Erice C, Bahr M, Flavahan K, de Jesus P, Kim J, Foss CA, Peloquin CA, Hammoud DA, Ordonez AA, Pardo CA, Jain SK. Ruiz-Bedoya CA, et al. Among authors: flavahan k. J Clin Invest. 2022 Mar 15;132(6):e155851. doi: 10.1172/JCI155851. J Clin Invest. 2022. PMID: 35085105 Free PMC article.
Dynamic 18F-Pretomanid PET imaging in animal models of TB meningitis and human studies.
Mota F, Ruiz-Bedoya CA, Tucker EW, Holt DP, De Jesus P, Lodge MA, Erice C, Chen X, Bahr M, Flavahan K, Kim J, Brosnan MK, Ordonez AA, Peloquin CA, Dannals RF, Jain SK. Mota F, et al. Among authors: flavahan k. Nat Commun. 2022 Dec 29;13(1):7974. doi: 10.1038/s41467-022-35730-3. Nat Commun. 2022. PMID: 36581633 Free PMC article.
Advances and Challenges in Molecular Imaging of Viral Infections.
Lau CY, Martinez-Orengo N, Lyndaker A, Flavahan K, Johnson RF, Shah S, Hammoud DA. Lau CY, et al. Among authors: flavahan k. J Infect Dis. 2023 Oct 3;228(Suppl 4):S270-S280. doi: 10.1093/infdis/jiad247. J Infect Dis. 2023. PMID: 37788495 Free PMC article. Review.
Linezolid does not improve bactericidal activity of rifampin-containing first-line regimens in animal models of TB meningitis.
Tucker EW, Ruiz-Bedoya CA, Mota F, Erice C, Kim J, de Jesus P, Jahdav R, Bahr M, Flavahan K, Chen X, Peloquin CA, Freundlich JS, Jain SK. Tucker EW, et al. Among authors: flavahan k. Int J Antimicrob Agents. 2024 Jan;63(1):107048. doi: 10.1016/j.ijantimicag.2023.107048. Epub 2023 Dec 5. Int J Antimicrob Agents. 2024. PMID: 38061419 Free article.
13 results