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Designer high-density lipoprotein particles enhance endothelial barrier function and suppress inflammation.
Lin YC, Swendeman S, Moreira IS, Ghosh A, Kuo A, Rosário-Ferreira N, Guo S, Culbertson A, Levesque MV, Cartier A, Seno T, Schmaier A, Galvani S, Inoue A, Parikh SM, FitzGerald GA, Zurakowski D, Liao M, Flaumenhaft R, Gümüş ZH, Hla T. Lin YC, et al. Among authors: flaumenhaft r. Sci Signal. 2024 Feb 20;17(824):eadg9256. doi: 10.1126/scisignal.adg9256. Epub 2024 Feb 20. Sci Signal. 2024. PMID: 38377179 Free PMC article.
PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury.
De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R. De Ceunynck K, et al. Among authors: flaumenhaft r. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E982-E991. doi: 10.1073/pnas.1718600115. Epub 2018 Jan 17. Proc Natl Acad Sci U S A. 2018. PMID: 29343648 Free PMC article.
Tie2 protects the vasculature against thrombus formation in systemic inflammation.
Higgins SJ, De Ceunynck K, Kellum JA, Chen X, Gu X, Chaudhry SA, Schulman S, Libermann TA, Lu S, Shapiro NI, Christiani DC, Flaumenhaft R, Parikh SM. Higgins SJ, et al. Among authors: flaumenhaft r. J Clin Invest. 2018 Apr 2;128(4):1471-1484. doi: 10.1172/JCI97488. Epub 2018 Mar 5. J Clin Invest. 2018. PMID: 29360642 Free PMC article. Clinical Trial.
Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19.
Schmaier AA, Pajares Hurtado GM, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Shapiro NI, Gerszten RE, Yu XG; MGH COVID-19 Collection and Processing Team; Peters KG, Flaumenhaft R, Parikh SM. Schmaier AA, et al. Among authors: flaumenhaft r. JCI Insight. 2021 Oct 22;6(20):e151527. doi: 10.1172/jci.insight.151527. JCI Insight. 2021. PMID: 34506304 Free PMC article.
Vasculopathy in COVID-19.
Flaumenhaft R, Enjyoji K, Schmaier AA. Flaumenhaft R, et al. Blood. 2022 Jul 21;140(3):222-235. doi: 10.1182/blood.2021012250. Blood. 2022. PMID: 34986238 Free PMC article. Review.
TMEM16E regulates endothelial cell procoagulant activity and thrombosis.
Schmaier AA, Anderson PF, Chen SM, El-Darzi E, Aivasovsky I, Kaushik MP, Sack KD, Hartzell HC, Parikh SM, Flaumenhaft R, Schulman S. Schmaier AA, et al. Among authors: flaumenhaft r. J Clin Invest. 2023 Jun 1;133(11):e163808. doi: 10.1172/JCI163808. J Clin Invest. 2023. PMID: 36951953 Free PMC article.
A polymer-based systemic hemostatic agent.
Gao Y, Sarode A, Kokoroskos N, Ukidve A, Zhao Z, Guo S, Flaumenhaft R, Gupta AS, Saillant N, Mitragotri S. Gao Y, et al. Among authors: flaumenhaft r. Sci Adv. 2020 Jul 31;6(31):eaba0588. doi: 10.1126/sciadv.aba0588. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32775633 Free PMC article.
Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19.
Schmaier AA, Hurtado GP, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Gerszten RE, Yu XG; MGH COVID-19 Collection and Processing Team; Peters K, Flaumenhaft R, Parikh SM. Schmaier AA, et al. Among authors: flaumenhaft r. medRxiv [Preprint]. 2021 May 17:2021.05.13.21257070. doi: 10.1101/2021.05.13.21257070. medRxiv. 2021. PMID: 34031665 Free PMC article. Updated. Preprint.
152 results