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Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.
Loo L, Waller MA, Moreno CL, Cole AJ, Stella AO, Pop OT, Jochum AK, Ali OH, Denes CE, Hamoudi Z, Chung F, Aggarwal A, Low JKK, Patel K, Siddiquee R, Kang T, Mathivanan S, Mackay JP, Jochum W, Flatz L, Hesselson D, Turville S, Neely GG. Loo L, et al. Among authors: flatz l. PLoS Biol. 2023 Feb 9;21(2):e3001967. doi: 10.1371/journal.pbio.3001967. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36757924 Free PMC article.
Prognostic role of gamma-glutamyl transferase in metastatic melanoma patients treated with immune checkpoint inhibitors.
Winter J, Lenders MM, Gassenmaier M, Forschner A, Leiter U, Weide B, Purde MT, Flatz L, Cozzio A, Röcken M, Garbe C, Eigentler TK, Wagner NB. Winter J, et al. Among authors: flatz l. Cancer Immunol Immunother. 2021 Apr;70(4):1089-1099. doi: 10.1007/s00262-020-02768-5. Epub 2020 Oct 28. Cancer Immunol Immunother. 2021. PMID: 33113003 Free PMC article.
Pretreatment metastatic growth rate determines clinical outcome of advanced melanoma patients treated with anti-PD-1 antibodies: a multicenter cohort study.
Wagner NB, Lenders MM, Kühl K, Reinhardt L, André F, Dudda M, Ring N, Ebel C, Stäger R, Zellweger C, Lang R, Paar M, Gussek P, Richtig G, Stürmer SH, Kimeswenger S, Oellinger A, Forschner A, Leiter U, Weide B, Gassenmaier M, Schraag A, Klumpp B, Hoetzenecker W, Berking C, Richtig E, Ziemer M, Mangana J, Terheyden P, Loquai C, Nguyen VA, Gebhardt C, Meier F, Diem S, Cozzio A, Flatz L, Röcken M, Garbe C, Eigentler TK. Wagner NB, et al. Among authors: flatz l. J Immunother Cancer. 2021 May;9(5):e002350. doi: 10.1136/jitc-2021-002350. J Immunother Cancer. 2021. PMID: 33986126 Free PMC article.
Association between Immune-Related Adverse Events and Survival in 319 Stage IV Melanoma Patients Treated with PD-1-Based Immunotherapy: An Approach Based on Clinical Chemistry.
Serna-Higuita LM, Amaral T, Forschner A, Leiter U, Flatz L, Seeber O, Thomas I, Garbe C, Eigentler TK, Martus P. Serna-Higuita LM, et al. Among authors: flatz l. Cancers (Basel). 2021 Dec 6;13(23):6141. doi: 10.3390/cancers13236141. Cancers (Basel). 2021. PMID: 34885249 Free PMC article.
TMB and BRAF mutation status are independent predictive factors in high-risk melanoma patients with adjuvant anti-PD-1 therapy.
Eckardt J, Schroeder C, Martus P, Armeanu-Ebinger S, Kelemen O, Gschwind A, Bonzheim I, Eigentler T, Amaral T, Ossowski S, Rieß O, Flatz L, Garbe C, Forschner A. Eckardt J, et al. Among authors: flatz l. J Cancer Res Clin Oncol. 2023 Feb;149(2):833-840. doi: 10.1007/s00432-022-03939-w. Epub 2022 Feb 22. J Cancer Res Clin Oncol. 2023. PMID: 35192052 Free PMC article.
EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy.
Amaral T, Pop OT, Chatziioannou E, Sinnberg T, Niessner H, Zhao J, Ring SS, Joerger M, Schroeder C, Armeanu-Ebinger S, Cozzio A, Leiter U, Thomas I, Jochum W, Garbe C, Forchhammer S, Levesque M, Mangana J, Hölzel M, Dummer R, Schürch CM, Forschner A, Flatz L. Amaral T, et al. Among authors: flatz l. J Am Acad Dermatol. 2023 Nov;89(5):1072-1074. doi: 10.1016/j.jaad.2023.06.057. Epub 2023 Jul 22. J Am Acad Dermatol. 2023. PMID: 37487833 No abstract available.
119 results