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Correlative light-electron microscopy methods to characterize the ultrastructural features of the replicative and dormant liver stages of Plasmodium parasites.
Mitchell G, Torres L, Fishbaugher ME, Lam M, Chuenchob V, Zalpuri R, Ramasubban S, Baxter CN, Flannery EL, Harupa A, Mikolajczak SA, Jorgens DM. Mitchell G, et al. Among authors: flannery el. Malar J. 2024 Feb 21;23(1):53. doi: 10.1186/s12936-024-04862-w. Malar J. 2024. PMID: 38383417 Free PMC article.
A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites.
Maher SP, Bakowski MA, Vantaux A, Flannery EL, Andolina C, Gupta M, Antonova-Koch Y, Argomaniz M, Cabrera-Mora M, Campo B, Chao AT, Chatterjee AK, Cheng WT, Chuenchob E, Cooper CA, Cottier K, Galinski MR, Harupa-Chung A, Ji H, Joseph SB, Lenz T, Lonardi S, Matheson J, Mikolajczak SA, Moeller T, Orban A, Padín-Irizarry V, Pan K, Péneau J, Prudhomme J, Roesch C, Ruberto AA, Sabnis SS, Saney CL, Sattabongkot J, Sereshki S, Suriyakan S, Ubalee R, Wang Y, Wasisakun P, Yin J, Popovici J, McNamara CW, Joyner CJ, Nosten F, Witkowski B, Le Roch KG, Kyle DE. Maher SP, et al. Among authors: flannery el. bioRxiv [Preprint]. 2024 Mar 25:2023.01.31.526483. doi: 10.1101/2023.01.31.526483. bioRxiv. 2024. PMID: 36778461 Free PMC article. Preprint.
Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine.
Flannery EL, Kangwanrangsan N, Chuenchob V, Roobsoong W, Fishbaugher M, Zhou K, Billman ZP, Martinson T, Olsen TM, Schäfer C, Campo B, Murphy SC, Mikolajczak SA, Kappe SHI, Sattabongkot J. Flannery EL, et al. Mol Ther Methods Clin Dev. 2022 Aug 2;26:427-440. doi: 10.1016/j.omtm.2022.07.016. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 36092359 Free PMC article.
Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections.
Gualdrón-López M, Díaz-Varela M, Zanghi G, Aparici-Herraiz I, Steel RWJ, Schäfer C, Cuscó P, Chuenchob V, Kangwangransan N, Billman ZP, Olsen TM, González JR, Roobsoong W, Sattabongkot J, Murphy SC, Mikolajczak SA, Borràs E, Sabidó E, Fernandez-Becerra C, Flannery EL, Kappe SHI, Del Portillo HA. Gualdrón-López M, et al. Among authors: flannery el. Mol Cell Proteomics. 2022 Oct;21(10):100406. doi: 10.1016/j.mcpro.2022.100406. Epub 2022 Aug 24. Mol Cell Proteomics. 2022. PMID: 36030044 Free PMC article.
A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection.
Schäfer C, Roobsoong W, Kangwanrangsan N, Bardelli M, Rawlinson TA, Dambrauskas N, Trakhimets O, Parthiban C, Goswami D, Reynolds LM, Kennedy SY, Flannery EL, Murphy SC, Sather DN, Draper SJ, Sattabongkot J, Mikolajczak SA, Kappe SHI. Schäfer C, et al. Among authors: flannery el. iScience. 2020 Aug 21;23(8):101381. doi: 10.1016/j.isci.2020.101381. Epub 2020 Jul 18. iScience. 2020. PMID: 32739836 Free PMC article.
Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target.
Alam MM, Sanchez-Azqueta A, Janha O, Flannery EL, Mahindra A, Mapesa K, Char AB, Sriranganadane D, Brancucci NMB, Antonova-Koch Y, Crouch K, Simwela NV, Millar SB, Akinwale J, Mitcheson D, Solyakov L, Dudek K, Jones C, Zapatero C, Doerig C, Nwakanma DC, Vázquez MJ, Colmenarejo G, Lafuente-Monasterio MJ, Leon ML, Godoi PHC, Elkins JM, Waters AP, Jamieson AG, Álvaro EF, Ranford-Cartwright LC, Marti M, Winzeler EA, Gamo FJ, Tobin AB. Alam MM, et al. Among authors: flannery el. Science. 2019 Aug 30;365(6456):eaau1682. doi: 10.1126/science.aau1682. Science. 2019. PMID: 31467193
Plasmodium vivax.
Flannery EL, Markus MB, Vaughan AM. Flannery EL, et al. Trends Parasitol. 2019 Jul;35(7):583-584. doi: 10.1016/j.pt.2019.04.005. Epub 2019 Jun 5. Trends Parasitol. 2019. PMID: 31176582 Review. No abstract available.
39 results