Flanagan T - Search Results

1

A Critical Overview of the Biological Effects of Excipients (Part I): Impact on Gastrointestinal Absorption.

Martinez MN, Sinko B, Wu F, Flanagan T, Borbás E, Tsakalozou E, Giacomini KM. Martinez MN, et al. Among authors: flanagan t. AAPS J. 2022 May 2;24(3):60. doi: 10.1208/s12248-022-00711-3. AAPS J. 2022. PMID: 35501614 Review.

2

Optimizing Clinical Drug Product Performance: Applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid.

Dickinson PA, Kesisoglou F, Flanagan T, Martinez MN, Mistry HB, Crison JR, Polli JE, Cruañes MT, Serajuddin ATM, Müllertz A, Cook JA, Selen A. Dickinson PA, et al. Among authors: flanagan t. J Pharm Sci. 2016 Nov;105(11):3243-3255. doi: 10.1016/j.xphs.2016.07.024. Epub 2016 Sep 19. J Pharm Sci. 2016. PMID: 27659159 Review.

3

Potential for pharmaceutical excipients to impact absorption: A mechanistic review for BCS Class 1 and 3 drugs.

Flanagan T. Flanagan T. Eur J Pharm Biopharm. 2019 Aug;141:130-138. doi: 10.1016/j.ejpb.2019.05.020. Epub 2019 May 22. Eur J Pharm Biopharm. 2019. PMID: 31128247 Review.

4

Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties. Case Study: Superdisintegrants.

Zarmpi P, Flanagan T, Meehan E, Mann J, Fotaki N. Zarmpi P, et al. Among authors: flanagan t. AAPS J. 2020 Feb 11;22(2):46. doi: 10.1208/s12248-019-0406-y. AAPS J. 2020. PMID: 32048079 Free PMC article.

5

Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties: Case Study-Hypromellose (HPMC).

Zarmpi P, Flanagan T, Meehan E, Mann J, Fotaki N. Zarmpi P, et al. Among authors: flanagan t. AAPS J. 2020 Feb 18;22(2):49. doi: 10.1208/s12248-019-0411-1. AAPS J. 2020. PMID: 32072317 Free PMC article.

6

Impact of Magnesium Stearate Presence and Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties.

Zarmpi P, Flanagan T, Meehan E, Mann J, Fotaki N. Zarmpi P, et al. Among authors: flanagan t. AAPS J. 2020 May 21;22(4):75. doi: 10.1208/s12248-020-00449-w. AAPS J. 2020. PMID: 32440810 Free PMC article.

7

Impact of Food and Drink Administration Vehicles on Paediatric Formulation Performance: Part 1-Effects on Solubility of Poorly Soluble Drugs.

Martir J, Flanagan T, Mann J, Fotaki N. Martir J, et al. Among authors: flanagan t. AAPS PharmSciTech. 2020 Jun 26;21(5):177. doi: 10.1208/s12249-020-01722-z. AAPS PharmSciTech. 2020. PMID: 32592045 Free PMC article.

8

Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report.

Parrott N, Suarez-Sharp S, Kesisoglou F, Pathak SM, Good D, Wagner C, Dallmann A, Mullin J, Patel N, Riedmaier AE, Mitra A, Raines K, Butler J, Kakhi M, Li M, Zhao Y, Tsakalozou E, Flanagan T, Dressman J, Pepin X. Parrott N, et al. Among authors: flanagan t. J Pharm Sci. 2021 Feb;110(2):584-593. doi: 10.1016/j.xphs.2020.09.058. Epub 2020 Oct 13. J Pharm Sci. 2021. PMID: 33058891

9

Impact of Food and Drink Administration Vehicles on Paediatric Formulation Performance Part 2: Dissolution of Montelukast Sodium and Mesalazine Formulations.

Martir J, Flanagan T, Mann J, Fotaki N. Martir J, et al. Among authors: flanagan t. AAPS PharmSciTech. 2020 Oct 15;21(7):287. doi: 10.1208/s12249-020-01815-9. AAPS PharmSciTech. 2020. PMID: 33063245 Free PMC article.

10

Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality: A Workshop Summary Report.

Mitra A, Suarez-Sharp S, Pepin XJH, Flanagan T, Zhao Y, Kotzagiorgis E, Parrott N, Sharan S, Tistaert C, Heimbach T, Zolnik B, Sjögren E, Wu F, Anand O, Kakar S, Li M, Veerasingham S, Kijima S, Lima Santos GM, Ning B, Raines K, Rullo G, Mandula H, Delvadia P, Dressman J, Dickinson PA, Babiskin A. Mitra A, et al. Among authors: flanagan t. J Pharm Sci. 2021 Feb;110(2):594-609. doi: 10.1016/j.xphs.2020.10.059. Epub 2020 Nov 3. J Pharm Sci. 2021. PMID: 33152375

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