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Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B.
Olivotto E, Vitellozzi R, Fernandez P, Falcieri E, Battistelli M, Burattini S, Facchini A, Flamigni F, Santi S, Facchini A, Borzi' RM. Olivotto E, et al. Among authors: flamigni f. J Cell Physiol. 2007 Feb;210(2):417-27. doi: 10.1002/jcp.20864. J Cell Physiol. 2007. PMID: 17096385
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