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Neuronal impact of patient-specific aberrant NRXN1α splicing.
Flaherty E, Zhu S, Barretto N, Cheng E, Deans PJM, Fernando MB, Schrode N, Francoeur N, Antoine A, Alganem K, Halpern M, Deikus G, Shah H, Fitzgerald M, Ladran I, Gochman P, Rapoport J, Tsankova NM, McCullumsmith R, Hoffman GE, Sebra R, Fang G, Brennand KJ. Flaherty E, et al. Nat Genet. 2019 Dec;51(12):1679-1690. doi: 10.1038/s41588-019-0539-z. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784728 Free PMC article.
Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.
Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, Aronow B, Fang G, Zhang B, Cotter D, Brennand KJ. Topol A, et al. Among authors: flaherty e. Transl Psychiatry. 2015 Oct 20;5(10):e662. doi: 10.1038/tp.2015.118. Transl Psychiatry. 2015. PMID: 26485546 Free PMC article.
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, Ho SM, MacDonald M, Hoffman GE, Roussos P, Zhang B, Hahn CG, Weng Z, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: flaherty e. Science. 2018 Dec 14;362(6420):eaat4311. doi: 10.1126/science.aat4311. Science. 2018. PMID: 30545851 Free PMC article.
CRISPR-based functional evaluation of schizophrenia risk variants.
Rajarajan P, Flaherty E, Akbarian S, Brennand KJ. Rajarajan P, et al. Among authors: flaherty e. Schizophr Res. 2020 Mar;217:26-36. doi: 10.1016/j.schres.2019.06.017. Epub 2019 Jul 3. Schizophr Res. 2020. PMID: 31277978 Free PMC article.
186 results