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Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL-12p70 production and mediate elevated effector functions in innate and adaptive immune cells.
Sköld AE, Mathan TSM, van Beek JJP, Flórez-Grau G, van den Beukel MD, Sittig SP, Wimmers F, Bakdash G, Schreibelt G, de Vries IJM. Sköld AE, et al. Cancer Immunol Immunother. 2018 Sep;67(9):1425-1436. doi: 10.1007/s00262-018-2204-2. Epub 2018 Jul 13. Cancer Immunol Immunother. 2018. PMID: 30019146 Free PMC article.
Human type 1 and type 2 conventional dendritic cells express indoleamine 2,3-dioxygenase 1 with functional effects on T cell priming.
Sittig SP, van Beek JJP, Flórez-Grau G, Weiden J, Buschow SI, van der Net MC, van Slooten R, Verbeek MM, Geurtz PBH, Textor J, Figdor CG, de Vries IJM, Schreibelt G. Sittig SP, et al. Eur J Immunol. 2021 Jun;51(6):1494-1504. doi: 10.1002/eji.202048580. Epub 2021 Mar 22. Eur J Immunol. 2021. PMID: 33675038 Free PMC article.
Recent Advances and Future Perspective of DC-Based Therapy in NSCLC.
van der Hoorn IAE, Flórez-Grau G, van den Heuvel MM, de Vries IJM, Piet B. van der Hoorn IAE, et al. Among authors: florez grau g. Front Immunol. 2021 Jun 28;12:704776. doi: 10.3389/fimmu.2021.704776. eCollection 2021. Front Immunol. 2021. PMID: 34262573 Free PMC article. Review.
Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion.
Le Gall C, Cammarata A, de Haas L, Ramos-Tomillero I, Cuenca-Escalona J, Schouren K, Wijfjes Z, Becker AMD, Bödder J, Dölen Y, de Vries IJM, Figdor CG, Flórez-Grau G, Verdoes M. Le Gall C, et al. Among authors: florez grau g. J Immunother Cancer. 2022 Apr;10(4):e004309. doi: 10.1136/jitc-2021-004309. J Immunother Cancer. 2022. PMID: 35428705 Free PMC article.
Guidelines for mouse and human DC generation.
Lutz MB, Ali S, Audiger C, Autenrieth SE, Berod L, Bigley V, Cyran L, Dalod M, Dörrie J, Dudziak D, Flórez-Grau G, Giusiano L, Godoy GJ, Heuer M, Krug AB, Lehmann CHK, Mayer CT, Naik SH, Scheu S, Schreibelt G, Segura E, Seré K, Sparwasser T, Tel J, Xu H, Zenke M. Lutz MB, et al. Among authors: florez grau g. Eur J Immunol. 2023 Nov;53(11):e2249816. doi: 10.1002/eji.202249816. Epub 2022 Oct 27. Eur J Immunol. 2023. PMID: 36303448 Free PMC article.
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