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Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.
Dhavale DD, Barclay AM, Borcik CG, Basore K, Berthold DA, Gordon IR, Liu J, Milchberg MH, O'Shea JY, Rau MJ, Smith Z, Sen S, Summers B, Smith J, Warmuth OA, Perrin RJ, Perlmutter JS, Chen Q, Fitzpatrick JAJ, Schwieters CD, Tajkhorshid E, Rienstra CM, Kotzbauer PT. Dhavale DD, et al. Among authors: fitzpatrick jaj. Nat Commun. 2024 Mar 29;15(1):2750. doi: 10.1038/s41467-024-46832-5. Nat Commun. 2024. PMID: 38553463 Free PMC article.
Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.
Li J, Moretti F, Hidvegi T, Sviben S, Fitzpatrick JAJ, Sundaramoorthi H, Pak SC, Silverman GA, Knapp B, Filipuzzi I, Alford J, Reece-Hoyes J, Nigsch F, Murphy LO, Nyfeler B, Perlmutter DH. Li J, et al. Among authors: fitzpatrick jaj. Cell Mol Gastroenterol Hepatol. 2024 Feb 7;17(6):1007-1024. doi: 10.1016/j.jcmgh.2024.02.006. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38336172 Free PMC article.
Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes.
Deveryshetty J, Chadda R, Mattice JR, Karunakaran S, Rau MJ, Basore K, Pokhrel N, Englander N, Fitzpatrick JAJ, Bothner B, Antony E. Deveryshetty J, et al. Among authors: fitzpatrick jaj. Nat Commun. 2023 Oct 5;14(1):6215. doi: 10.1038/s41467-023-41993-1. Nat Commun. 2023. PMID: 37798272 Free PMC article.
124 results