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PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours.
Davern M, Fitzgerald MC, Buckley CE, Heeran AB, Donlon NE, McGrath J, O' Connell F, Deshpande MR, Hayes C, MacDonald J, Sheppard AD, Reynolds JV, Maher SG, Lynam-Lennon N, Murphy B, Lysaght J. Davern M, et al. Among authors: fitzgerald mc. Transl Oncol. 2022 May;19:101381. doi: 10.1016/j.tranon.2022.101381. Epub 2022 Mar 1. Transl Oncol. 2022. PMID: 35245832 Free PMC article.
Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.
Mansfield CR, Quan B, Chirgwin ME, Eduful B, Hughes PF, Neveu G, Sylvester K, Ryan DH, Kafsack BFC, Haystead TAJ, Leahy JW, Fitzgerald MC, Derbyshire ER. Mansfield CR, et al. Among authors: fitzgerald mc. Cell Chem Biol. 2024 Apr 18;31(4):729-742.e13. doi: 10.1016/j.chembiol.2024.02.008. Epub 2024 Mar 15. Cell Chem Biol. 2024. PMID: 38492573
Hospitalisations and in-hospital deaths following moderate to severe traumatic brain injury in Australia, 2015-20: a registry data analysis for the Australian Traumatic Brain Injury National Data (ATBIND) project.
O'Reilly GM, Curtis K, Mitra B, Kim Y, Afroz A, Hunter K, Ryder C, Hendrie DV, Rushworth N, Tee J, D'Angelo S, Solly E, Bhattacharya O, Fitzgerald MC. O'Reilly GM, et al. Among authors: fitzgerald mc. Med J Aust. 2023 Oct 2;219(7):316-324. doi: 10.5694/mja2.52055. Epub 2023 Jul 31. Med J Aust. 2023. PMID: 37524539
Prehospital Tranexamic Acid for Severe Trauma.
PATCH-Trauma Investigators and the ANZICS Clinical Trials Group; Gruen RL, Mitra B, Bernard SA, McArthur CJ, Burns B, Gantner DC, Maegele M, Cameron PA, Dicker B, Forbes AB, Hurford S, Martin CA, Mazur SM, Medcalf RL, Murray LJ, Myles PS, Ng SJ, Pitt V, Rashford S, Reade MC, Swain AH, Trapani T, Young PJ. PATCH-Trauma Investigators and the ANZICS Clinical Trials Group, et al. N Engl J Med. 2023 Jul 13;389(2):127-136. doi: 10.1056/NEJMoa2215457. Epub 2023 Jun 14. N Engl J Med. 2023. PMID: 37314244 Clinical Trial.
203 results