Fishwick CW - Search Results

1

Applications of structure-based design to antibacterial drug discovery.

Cain R, Narramore S, McPhillie M, Simmons K, Fishwick CW. Cain R, et al. Among authors: fishwick cw. Bioorg Chem. 2014 Aug;55:69-76. doi: 10.1016/j.bioorg.2014.05.008. Epub 2014 Jun 2. Bioorg Chem. 2014. PMID: 24962384 Review.

2

Spatial requirements of the antagonist binding site of the NK2 receptor.

Ali MA, Bhogal N, Fishwick CW, Findlay JB. Ali MA, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2001 Mar 26;11(6):819-22. doi: 10.1016/s0960-894x(01)00074-9. Bioorg Med Chem Lett. 2001. PMID: 11277528

3

Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD.

Horton JR, Bostock JM, Chopra I, Hesse L, Phillips SE, Adams DJ, Johnson AP, Fishwick CW. Horton JR, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2003 May 5;13(9):1557-60. doi: 10.1016/s0960-894x(03)00176-8. Bioorg Med Chem Lett. 2003. PMID: 12699754

4

The first de novo designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.

Heikkilä T, Thirumalairajan S, Davies M, Parsons MR, McConkey AG, Fishwick CW, Johnson AP. Heikkilä T, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2006 Jan 1;16(1):88-92. doi: 10.1016/j.bmcl.2005.09.045. Epub 2005 Oct 19. Bioorg Med Chem Lett. 2006. PMID: 16236496

5

2-Aminotetralones: novel inhibitors of MurA and MurZ.

Dunsmore CJ, Miller K, Blake KL, Patching SG, Henderson PJ, Garnett JA, Stubbings WJ, Phillips SE, Palestrant DJ, Angeles Jde L, Leeds JA, Chopra I, Fishwick CW. Dunsmore CJ, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1730-4. doi: 10.1016/j.bmcl.2008.01.089. Epub 2008 Jan 30. Bioorg Med Chem Lett. 2008. PMID: 18261901

6

The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors.

Blake KL, O'Neill AJ, Mengin-Lecreulx D, Henderson PJ, Bostock JM, Dunsmore CJ, Simmons KJ, Fishwick CW, Leeds JA, Chopra I. Blake KL, et al. Among authors: fishwick cw. Mol Microbiol. 2009 Apr;72(2):335-43. doi: 10.1111/j.1365-2958.2009.06648.x. Epub 2009 Mar 3. Mol Microbiol. 2009. PMID: 19298367 Free article.

7

Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases.

Davies M, Heikkilä T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Davies M, et al. Among authors: fishwick cw. J Med Chem. 2009 May 14;52(9):2683-93. doi: 10.1021/jm800963t. J Med Chem. 2009. PMID: 19351152

8

Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening.

Yi Mok N, Chadwick J, Kellett KA, Hooper NM, Johnson AP, Fishwick CW. Yi Mok N, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6770-4. doi: 10.1016/j.bmcl.2009.09.103. Epub 2009 Oct 2. Bioorg Med Chem Lett. 2009. PMID: 19854048

9

A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH.

Cowen D, Bedingfield P, McConkey GA, Fishwick CW, Johnson AP. Cowen D, et al. Among authors: fishwick cw. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1284-7. doi: 10.1016/j.bmcl.2009.11.079. Epub 2009 Nov 27. Bioorg Med Chem Lett. 2010. PMID: 20034791

10

Structure-based discovery of antibacterial drugs.

Simmons KJ, Chopra I, Fishwick CW. Simmons KJ, et al. Among authors: fishwick cw. Nat Rev Microbiol. 2010 Jul;8(7):501-10. doi: 10.1038/nrmicro2349. Nat Rev Microbiol. 2010. PMID: 20551974 Review.

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