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Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB. Preston S, et al. Among authors: fisher gm. FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7. FASEB J. 2017. PMID: 28687609
Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.
Trenholme K, Marek L, Duffy S, Pradel G, Fisher G, Hansen FK, Skinner-Adams TS, Butterworth A, Ngwa CJ, Moecking J, Goodman CD, McFadden GI, Sumanadasa SD, Fairlie DP, Avery VM, Kurz T, Andrews KT. Trenholme K, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3666-78. doi: 10.1128/AAC.02721-13. Epub 2014 Apr 14. Antimicrob Agents Chemother. 2014. PMID: 24733477 Free PMC article.
Drug repurposing and human parasitic protozoan diseases.
Andrews KT, Fisher G, Skinner-Adams TS. Andrews KT, et al. Int J Parasitol Drugs Drug Resist. 2014 Mar 24;4(2):95-111. doi: 10.1016/j.ijpddr.2014.02.002. eCollection 2014 Aug. Int J Parasitol Drugs Drug Resist. 2014. PMID: 25057459 Free PMC article. Review.
Defining the targets of antiparasitic compounds.
Skinner-Adams TS, Sumanadasa SD, Fisher GM, Davis RA, Doolan DL, Andrews KT. Skinner-Adams TS, et al. Among authors: fisher gm. Drug Discov Today. 2016 May;21(5):725-39. doi: 10.1016/j.drudis.2016.01.002. Epub 2016 Jan 16. Drug Discov Today. 2016. PMID: 26784142 Review.
59 results