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A fragment-like approach to PYCR1 inhibition.
Milne K, Sun J, Zaal EA, Mowat J, Celie PHN, Fish A, Berkers CR, Forlani G, Loayza-Puch F, Jamieson C, Agami R. Milne K, et al. Among authors: fish a. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2626-2631. doi: 10.1016/j.bmcl.2019.07.047. Epub 2019 Jul 25. Bioorg Med Chem Lett. 2019. PMID: 31362921 Free article.
The first step of peptide selection in antigen presentation by MHC class I molecules.
Garstka MA, Fish A, Celie PH, Joosten RP, Janssen GM, Berlin I, Hoppes R, Stadnik M, Janssen L, Ovaa H, van Veelen PA, Perrakis A, Neefjes J. Garstka MA, et al. Among authors: fish a. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1505-10. doi: 10.1073/pnas.1416543112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605945 Free PMC article.
Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening.
Elbatsh AMO, Haarhuis JHI, Petela N, Chapard C, Fish A, Celie PH, Stadnik M, Ristic D, Wyman C, Medema RH, Nasmyth K, Rowland BD. Elbatsh AMO, et al. Among authors: fish a. Mol Cell. 2016 Feb 18;61(4):575-588. doi: 10.1016/j.molcel.2016.01.025. Mol Cell. 2016. PMID: 26895426 Free PMC article.
The Soluble Periplasmic Domains of Escherichia coli Cell Division Proteins FtsQ/FtsB/FtsL Form a Trimeric Complex with Submicromolar Affinity.
Glas M, van den Berg van Saparoea HB, McLaughlin SH, Roseboom W, Liu F, Koningstein GM, Fish A, den Blaauwen T, Heck AJ, de Jong L, Bitter W, de Esch IJ, Luirink J. Glas M, et al. Among authors: fish a. J Biol Chem. 2015 Aug 28;290(35):21498-509. doi: 10.1074/jbc.M115.654756. Epub 2015 Jul 9. J Biol Chem. 2015. PMID: 26160297 Free PMC article.
Fluorescence-guided tumor detection with a novel anti-EpCAM targeted antibody fragment: Preclinical validation.
Boogerd LSF, Boonstra MC, Prevoo HAJM, Handgraaf HJM, Kuppen PJK, van de Velde CJH, Fish A, Cordfunke RA, Valentijn ARPM, Terwisscha van Scheltinga AG, MacDonald GC, Cizeau J, Premsukh A, Vinkenburg van Slooten ML, Burggraaf J, Sier CFM, Vahrmeijer AL. Boogerd LSF, et al. Among authors: fish a. Surg Oncol. 2019 Mar;28:1-8. doi: 10.1016/j.suronc.2018.10.004. Epub 2018 Oct 23. Surg Oncol. 2019. PMID: 30851880
Sharp kinking of a coiled-coil in MutS allows DNA binding and release.
Bhairosing-Kok D, Groothuizen FS, Fish A, Dharadhar S, Winterwerp HHK, Sixma TK. Bhairosing-Kok D, et al. Among authors: fish a. Nucleic Acids Res. 2019 Sep 19;47(16):8888-8898. doi: 10.1093/nar/gkz649. Nucleic Acids Res. 2019. PMID: 31372631 Free PMC article.
310 results