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Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels.
de la Roche J, Angsutararux P, Kempf H, Janan M, Bolesani E, Thiemann S, Wojciechowski D, Coffee M, Franke A, Schwanke K, Leffler A, Luanpitpong S, Issaragrisil S, Fischer M, Zweigerdt R. de la Roche J, et al. Among authors: fischer m. Sci Rep. 2019 Aug 1;9(1):11173. doi: 10.1038/s41598-019-47632-4. Sci Rep. 2019. PMID: 31371804 Free PMC article.
Lactate is a potent inhibitor of the capsaicin receptor TRPV1.
de la Roche J, Walther I, Leonow W, Hage A, Eberhardt M, Fischer M, Reeh PW, Sauer S, Leffler A. de la Roche J, et al. Among authors: fischer m. Sci Rep. 2016 Nov 9;6:36740. doi: 10.1038/srep36740. Sci Rep. 2016. PMID: 27827430 Free PMC article.
EBIO Does Not Induce Cardiomyogenesis in Human Pluripotent Stem Cells but Modulates Cardiac Subtype Enrichment by Lineage-Selective Survival.
Jara-Avaca M, Kempf H, Rückert M, Robles-Diaz D, Franke A, de la Roche J, Fischer M, Malan D, Sasse P, Solodenko W, Dräger G, Kirschning A, Martin U, Zweigerdt R. Jara-Avaca M, et al. Among authors: fischer m. Stem Cell Reports. 2017 Feb 14;8(2):305-317. doi: 10.1016/j.stemcr.2016.12.012. Epub 2017 Jan 12. Stem Cell Reports. 2017. PMID: 28089668 Free PMC article.
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture.
Halloin C, Schwanke K, Löbel W, Franke A, Szepes M, Biswanath S, Wunderlich S, Merkert S, Weber N, Osten F, de la Roche J, Polten F, Christoph Wollert K, Kraft T, Fischer M, Martin U, Gruh I, Kempf H, Zweigerdt R. Halloin C, et al. Among authors: fischer m. Stem Cell Reports. 2019 Aug 13;13(2):366-379. doi: 10.1016/j.stemcr.2019.06.004. Epub 2019 Jul 25. Stem Cell Reports. 2019. PMID: 31353227 Free PMC article.
Advanced Single-Cell Mapping Reveals that in hESC Cardiomyocytes Contraction Kinetics and Action Potential Are Independent of Myosin Isoform.
Weber N, Kowalski K, Holler T, Radocaj A, Fischer M, Thiemann S, de la Roche J, Schwanke K, Piep B, Peschel N, Krumm U, Lingk A, Wendland M, Greten S, Schmitto JD, Ismail I, Warnecke G, Zywietz U, Chichkov B, Meißner J, Haverich A, Martin U, Brenner B, Zweigerdt R, Kraft T. Weber N, et al. Among authors: fischer m. Stem Cell Reports. 2020 May 12;14(5):788-802. doi: 10.1016/j.stemcr.2020.03.015. Epub 2020 Apr 16. Stem Cell Reports. 2020. PMID: 32302556 Free PMC article.
Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture.
Kempf H, Olmer R, Kropp C, Rückert M, Jara-Avaca M, Robles-Diaz D, Franke A, Elliott DA, Wojciechowski D, Fischer M, Roa Lara A, Kensah G, Gruh I, Haverich A, Martin U, Zweigerdt R. Kempf H, et al. Among authors: fischer m. Stem Cell Reports. 2014 Dec 9;3(6):1132-46. doi: 10.1016/j.stemcr.2014.09.017. Epub 2014 Oct 30. Stem Cell Reports. 2014. PMID: 25454631 Free PMC article.
Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes.
Weber N, Schwanke K, Greten S, Wendland M, Iorga B, Fischer M, Geers-Knörr C, Hegermann J, Wrede C, Fiedler J, Kempf H, Franke A, Piep B, Pfanne A, Thum T, Martin U, Brenner B, Zweigerdt R, Kraft T. Weber N, et al. Among authors: fischer m. Basic Res Cardiol. 2016 Nov;111(6):68. doi: 10.1007/s00395-016-0587-9. Epub 2016 Oct 14. Basic Res Cardiol. 2016. PMID: 27743117
6,076 results