Fischer H - Search Results

1

DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermis.

Beck MA, Fischer H, Grabner LM, Groffics T, Winter M, Tangermann S, Meischel T, Zaussinger-Haas B, Wagner P, Fischer C, Folie C, Arand J, Schöfer C, Ramsahoye B, Lagger S, Machat G, Eisenwort G, Schneider S, Podhornik A, Kothmayer M, Reichart U, Glösmann M, Tamir I, Mildner M, Sheibani-Tezerji R, Kenner L, Petzelbauer P, Egger G, Sibilia M, Ablasser A, Seiser C. Beck MA, et al. Among authors: fischer c, fischer h. EMBO J. 2021 Nov 15;40(22):e108234. doi: 10.15252/embj.2021108234. Epub 2021 Sep 29. EMBO J. 2021. PMID: 34586646 Free PMC article.

2

DNase 2 is the main DNA-degrading enzyme of the stratum corneum.

Fischer H, Scherz J, Szabo S, Mildner M, Benarafa C, Torriglia A, Tschachler E, Eckhart L. Fischer H, et al. PLoS One. 2011 Mar 1;6(3):e17581. doi: 10.1371/journal.pone.0017581. PLoS One. 2011. PMID: 21390259 Free PMC article.

3

DNase1L2 degrades nuclear DNA during corneocyte formation.

Fischer H, Eckhart L, Mildner M, Jaeger K, Buchberger M, Ghannadan M, Tschachler E. Fischer H, et al. J Invest Dermatol. 2007 Jan;127(1):24-30. doi: 10.1038/sj.jid.5700503. Epub 2006 Aug 10. J Invest Dermatol. 2007. PMID: 16902420 Free article.

4

The caspase-1 inhibitor CARD18 is specifically expressed during late differentiation of keratinocytes and its expression is lost in lichen planus.

Qin H, Jin J, Fischer H, Mildner M, Gschwandtner M, Mlitz V, Eckhart L, Tschachler E. Qin H, et al. Among authors: fischer h. J Dermatol Sci. 2017 Aug;87(2):176-182. doi: 10.1016/j.jdermsci.2017.04.015. Epub 2017 May 1. J Dermatol Sci. 2017. PMID: 28506683

5

Histidase expression in human epidermal keratinocytes: regulation by differentiation status and all-trans retinoic acid.

Eckhart L, Schmidt M, Mildner M, Mlitz V, Abtin A, Ballaun C, Fischer H, Mrass P, Tschachler E. Eckhart L, et al. Among authors: fischer h. J Dermatol Sci. 2008 Jun;50(3):209-15. doi: 10.1016/j.jdermsci.2007.12.009. Epub 2008 Feb 15. J Dermatol Sci. 2008. PMID: 18280705

6

Cytosolic DNA sensing through cGAS and STING is inactivated by gene mutations in pangolins.

Fischer H, Tschachler E, Eckhart L. Fischer H, et al. Apoptosis. 2020 Aug;25(7-8):474-480. doi: 10.1007/s10495-020-01614-4. Apoptosis. 2020. PMID: 32533513 Free PMC article.

7

Mechanisms and emerging functions of DNA degradation in the epidermis.

Eckhart L, Fischer H, Tschachler E. Eckhart L, et al. Among authors: fischer h. Front Biosci (Landmark Ed). 2012 Jun 1;17(7):2461-75. doi: 10.2741/4065. Front Biosci (Landmark Ed). 2012. PMID: 22652792 Free article. Review.

8

Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis.

Fischer H, Rossiter H, Ghannadan M, Jaeger K, Barresi C, Declercq W, Tschachler E, Eckhart L. Fischer H, et al. Differentiation. 2005 Oct;73(8):406-13. doi: 10.1111/j.1432-0436.2005.00046.x. Differentiation. 2005. PMID: 16316411

9

Pangolins Lack IFIH1/MDA5, a Cytoplasmic RNA Sensor That Initiates Innate Immune Defense Upon Coronavirus Infection.

Fischer H, Tschachler E, Eckhart L. Fischer H, et al. Front Immunol. 2020 May 8;11:939. doi: 10.3389/fimmu.2020.00939. eCollection 2020. Front Immunol. 2020. PMID: 32574256 Free PMC article.

10

Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis.

Fischer H, Buchberger M, Napirei M, Tschachler E, Eckhart L. Fischer H, et al. Sci Rep. 2017 Jul 25;7(1):6433. doi: 10.1038/s41598-017-06652-8. Sci Rep. 2017. PMID: 28743926 Free PMC article.

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