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A gut-derived metabolite alters brain activity and anxiety behaviour in mice.
Needham BD, Funabashi M, Adame MD, Wang Z, Boktor JC, Haney J, Wu WL, Rabut C, Ladinsky MS, Hwang SJ, Guo Y, Zhu Q, Griffiths JA, Knight R, Bjorkman PJ, Shapiro MG, Geschwind DH, Holschneider DP, Fischbach MA, Mazmanian SK. Needham BD, et al. Among authors: fischbach ma. Nature. 2022 Feb;602(7898):647-653. doi: 10.1038/s41586-022-04396-8. Epub 2022 Feb 14. Nature. 2022. PMID: 35165440 Free PMC article.
Diet rapidly and reproducibly alters the human gut microbiome.
David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, Ling AV, Devlin AS, Varma Y, Fischbach MA, Biddinger SB, Dutton RJ, Turnbaugh PJ. David LA, et al. Among authors: fischbach ma. Nature. 2014 Jan 23;505(7484):559-63. doi: 10.1038/nature12820. Epub 2013 Dec 11. Nature. 2014. PMID: 24336217 Free PMC article. Clinical Trial.
Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Funabashi M, Taketani M, Donia MS, Nayfach S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voigt CA, Fischbach MA. Guo CJ, et al. Among authors: fischbach ma. Cell. 2017 Jan 26;168(3):517-526.e18. doi: 10.1016/j.cell.2016.12.021. Epub 2017 Jan 19. Cell. 2017. PMID: 28111075 Free PMC article.
Skin microbiota-host interactions.
Chen YE, Fischbach MA, Belkaid Y. Chen YE, et al. Among authors: fischbach ma. Nature. 2018 Jan 24;553(7689):427-436. doi: 10.1038/nature25177. Nature. 2018. PMID: 29364286 Free PMC article. Review.
A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors.
Nemet I, Saha PP, Gupta N, Zhu W, Romano KA, Skye SM, Cajka T, Mohan ML, Li L, Wu Y, Funabashi M, Ramer-Tait AE, Naga Prasad SV, Fiehn O, Rey FE, Tang WHW, Fischbach MA, DiDonato JA, Hazen SL. Nemet I, et al. Among authors: fischbach ma. Cell. 2020 Mar 5;180(5):862-877.e22. doi: 10.1016/j.cell.2020.02.016. Cell. 2020. PMID: 32142679 Free PMC article.
A metabolic pathway for bile acid dehydroxylation by the gut microbiome.
Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA. Funabashi M, et al. Among authors: fischbach ma. Nature. 2020 Jun;582(7813):566-570. doi: 10.1038/s41586-020-2396-4. Epub 2020 Jun 17. Nature. 2020. PMID: 32555455 Free PMC article.
Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome.
Nayfach S, Páez-Espino D, Call L, Low SJ, Sberro H, Ivanova NN, Proal AD, Fischbach MA, Bhatt AS, Hugenholtz P, Kyrpides NC. Nayfach S, et al. Among authors: fischbach ma. Nat Microbiol. 2021 Jul;6(7):960-970. doi: 10.1038/s41564-021-00928-6. Epub 2021 Jun 24. Nat Microbiol. 2021. PMID: 34168315 Free PMC article.
A metabolomics pipeline for the mechanistic interrogation of the gut microbiome.
Han S, Van Treuren W, Fischer CR, Merrill BD, DeFelice BC, Sanchez JM, Higginbottom SK, Guthrie L, Fall LA, Dodd D, Fischbach MA, Sonnenburg JL. Han S, et al. Among authors: fischbach ma. Nature. 2021 Jul;595(7867):415-420. doi: 10.1038/s41586-021-03707-9. Epub 2021 Jul 14. Nature. 2021. PMID: 34262212 Free PMC article.
294 results