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Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy.
Beaulieu ME, Jauset T, Massó-Vallés D, Martínez-Martín S, Rahl P, Maltais L, Zacarias-Fluck MF, Casacuberta-Serra S, Serrano Del Pozo E, Fiore C, Foradada L, Cano VC, Sánchez-Hervás M, Guenther M, Romero Sanz E, Oteo M, Tremblay C, Martín G, Letourneau D, Montagne M, Morcillo Alonso MÁ, Whitfield JR, Lavigne P, Soucek L. Beaulieu ME, et al. Among authors: fiore c. Sci Transl Med. 2019 Mar 20;11(484):eaar5012. doi: 10.1126/scitranslmed.aar5012. Sci Transl Med. 2019. PMID: 30894502 Free PMC article.
Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist.
McKeown MR, Corces MR, Eaton ML, Fiore C, Lee E, Lopez JT, Chen MW, Smith D, Chan SM, Koenig JL, Austgen K, Guenther MG, Orlando DA, Lovén J, Fritz CC, Majeti R. McKeown MR, et al. Among authors: fiore c. Cancer Discov. 2017 Oct;7(10):1136-1153. doi: 10.1158/2159-8290.CD-17-0399. Epub 2017 Jul 20. Cancer Discov. 2017. PMID: 28729405 Free PMC article.
Sponge-derived matter is assimilated by coral holobionts.
Reigel AM, Easson CG, Apprill A, Freeman CJ, Bartley MM, Fiore CL. Reigel AM, et al. Among authors: fiore cl. Commun Biol. 2024 Feb 2;7(1):146. doi: 10.1038/s42003-024-05836-z. Commun Biol. 2024. PMID: 38308082 Free PMC article.
450 results