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Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation.
Zwergel C, Fioravanti R, Stazi G, Sarno F, Battistelli C, Romanelli A, Nebbioso A, Mendes E, Paulo A, Strippoli R, Tripodi M, Pechalrieu D, Arimondo PB, De Luca T, Del Bufalo D, Trisciuoglio D, Altucci L, Valente S, Mai A. Zwergel C, et al. Among authors: fioravanti r. Cancers (Basel). 2020 Feb 14;12(2):447. doi: 10.3390/cancers12020447. Cancers (Basel). 2020. PMID: 32075099 Free PMC article.
Molecular Docking Assessment of Cathinones as 5-HT2AR Ligands: Developing of Predictive Structure-Based Bioactive Conformations and Three-Dimensional Structure-Activity Relationships Models for Future Recognition of Abuse Drugs.
Tomašević N, Vujović M, Kostić E, Ragavendran V, Arsić B, Matić SL, Božović M, Fioravanti R, Proia E, Ragno R, Mladenović M. Tomašević N, et al. Among authors: fioravanti r. Molecules. 2023 Aug 24;28(17):6236. doi: 10.3390/molecules28176236. Molecules. 2023. PMID: 37687065 Free PMC article.
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Zwergel C, Schnekenburger M, Sarno F, Battistelli C, Manara MC, Stazi G, Mazzone R, Fioravanti R, Gros C, Ausseil F, Florean C, Nebbioso A, Strippoli R, Ushijima T, Scotlandi K, Tripodi M, Arimondo PB, Altucci L, Diederich M, Mai A, Valente S. Zwergel C, et al. Among authors: fioravanti r. Clin Epigenetics. 2019 May 6;11(1):68. doi: 10.1186/s13148-019-0663-8. Clin Epigenetics. 2019. PMID: 31060628 Free PMC article.
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype.
Stazi G, Taglieri L, Nicolai A, Romanelli A, Fioravanti R, Morrone S, Sabatino M, Ragno R, Taurone S, Nebbioso M, Carletti R, Artico M, Valente S, Scarpa S, Mai A. Stazi G, et al. Among authors: fioravanti r. Clin Epigenetics. 2019 Dec 2;11(1):173. doi: 10.1186/s13148-019-0763-5. Clin Epigenetics. 2019. PMID: 31791385 Free PMC article. Retracted.
Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation.
Fioravanti R, Romanelli A, Mautone N, Di Bello E, Rovere A, Corinti D, Zwergel C, Valente S, Rotili D, Botrugno OA, Dessanti P, Vultaggio S, Vianello P, Cappa A, Binda C, Mattevi A, Minucci S, Mercurio C, Varasi M, Mai A. Fioravanti R, et al. ChemMedChem. 2020 Apr 3;15(7):643-658. doi: 10.1002/cmdc.201900730. Epub 2020 Feb 14. ChemMedChem. 2020. PMID: 32003940 Free PMC article.
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation.
Ravasio R, Ceccacci E, Nicosia L, Hosseini A, Rossi PL, Barozzi I, Fornasari L, Zuffo RD, Valente S, Fioravanti R, Mercurio C, Varasi M, Mattevi A, Mai A, Pavesi G, Bonaldi T, Minucci S. Ravasio R, et al. Among authors: fioravanti r. Sci Adv. 2020 Apr 8;6(15):eaax2746. doi: 10.1126/sciadv.aax2746. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32284990 Free PMC article.
Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
Romanelli A, Stazi G, Fioravanti R, Zwergel C, Di Bello E, Pomella S, Perrone C, Battistelli C, Strippoli R, Tripodi M, Del Bufalo D, Rota R, Trisciuoglio D, Mai A, Valente S. Romanelli A, et al. Among authors: fioravanti r. ACS Med Chem Lett. 2020 Mar 19;11(5):977-983. doi: 10.1021/acsmedchemlett.0c00014. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435414 Free PMC article.
104 results