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Metabolic reprogramming of natural killer cells in obesity limits antitumor responses.
Michelet X, Dyck L, Hogan A, Loftus RM, Duquette D, Wei K, Beyaz S, Tavakkoli A, Foley C, Donnelly R, O'Farrelly C, Raverdeau M, Vernon A, Pettee W, O'Shea D, Nikolajczyk BS, Mills KHG, Brenner MB, Finlay D, Lynch L. Michelet X, et al. Among authors: finlay d. Nat Immunol. 2018 Dec;19(12):1330-1340. doi: 10.1038/s41590-018-0251-7. Epub 2018 Nov 12. Nat Immunol. 2018. PMID: 30420624
Glucose, glycolysis and lymphocyte responses.
Donnelly RP, Finlay DK. Donnelly RP, et al. Mol Immunol. 2015 Dec;68(2 Pt C):513-9. doi: 10.1016/j.molimm.2015.07.034. Epub 2015 Aug 7. Mol Immunol. 2015. PMID: 26260211 Review.
Metabolic regulation of natural killer cells.
Finlay DK. Finlay DK. Biochem Soc Trans. 2015 Aug;43(4):758-62. doi: 10.1042/BST20150116. Epub 2015 Aug 3. Biochem Soc Trans. 2015. PMID: 26551725 Review.
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway.
Viel S, Marçais A, Guimaraes FS, Loftus R, Rabilloud J, Grau M, Degouve S, Djebali S, Sanlaville A, Charrier E, Bienvenu J, Marie JC, Caux C, Marvel J, Town L, Huntington ND, Bartholin L, Finlay D, Smyth MJ, Walzer T. Viel S, et al. Among authors: finlay d. Sci Signal. 2016 Feb 16;9(415):ra19. doi: 10.1126/scisignal.aad1884. Sci Signal. 2016. PMID: 26884601
Glucose represses dendritic cell-induced T cell responses.
Lawless SJ, Kedia-Mehta N, Walls JF, McGarrigle R, Convery O, Sinclair LV, Navarro MN, Murray J, Finlay DK. Lawless SJ, et al. Nat Commun. 2017 May 30;8:15620. doi: 10.1038/ncomms15620. Nat Commun. 2017. PMID: 28555668 Free PMC article.
482 results