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Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs.
Manganelli V, Matarrese P, Antonioli M, Gambardella L, Vescovo T, Gretzmeier C, Longo A, Capozzi A, Recalchi S, Riitano G, Misasi R, Dengjel J, Malorni W, Fimia GM, Sorice M, Garofalo T. Manganelli V, et al. Among authors: fimia gm. Autophagy. 2021 Sep;17(9):2528-2548. doi: 10.1080/15548627.2020.1834207. Epub 2020 Oct 23. Autophagy. 2021. PMID: 33034545 Free PMC article.
Tissue transglutaminase is a multifunctional BH3-only protein.
Rodolfo C, Mormone E, Matarrese P, Ciccosanti F, Farrace MG, Garofano E, Piredda L, Fimia GM, Malorni W, Piacentini M. Rodolfo C, et al. Among authors: fimia gm. J Biol Chem. 2004 Dec 24;279(52):54783-92. doi: 10.1074/jbc.M410938200. Epub 2004 Oct 12. J Biol Chem. 2004. PMID: 15485857 Free article.
Ambra1 regulates autophagy and development of the nervous system.
Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, Nardacci R, Corazzari M, Fuoco C, Ucar A, Schwartz P, Gruss P, Piacentini M, Chowdhury K, Cecconi F. Fimia GM, et al. Nature. 2007 Jun 28;447(7148):1121-5. doi: 10.1038/nature05925. Epub 2007 Jun 24. Nature. 2007. PMID: 17589504
A novel role for autophagy in neurodevelopment.
Cecconi F, Di Bartolomeo S, Nardacci R, Fuoco C, Corazzari M, Giunta L, Romagnoli A, Stoykova A, Chowdhury K, Fimia GM, Piacentini M. Cecconi F, et al. Among authors: fimia gm. Autophagy. 2007 Sep-Oct;3(5):506-8. doi: 10.4161/auto.4616. Epub 2007 Jun 21. Autophagy. 2007. PMID: 17622796
Transglutaminase 2 is involved in autophagosome maturation.
D'Eletto M, Farrace MG, Falasca L, Reali V, Oliverio S, Melino G, Griffin M, Fimia GM, Piacentini M. D'Eletto M, et al. Among authors: fimia gm. Autophagy. 2009 Nov;5(8):1145-54. doi: 10.4161/auto.5.8.10040. Autophagy. 2009. PMID: 19955852
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.
Di Bartolomeo S, Corazzari M, Nazio F, Oliverio S, Lisi G, Antonioli M, Pagliarini V, Matteoni S, Fuoco C, Giunta L, D'Amelio M, Nardacci R, Romagnoli A, Piacentini M, Cecconi F, Fimia GM. Di Bartolomeo S, et al. Among authors: fimia gm. J Cell Biol. 2010 Oct 4;191(1):155-68. doi: 10.1083/jcb.201002100. J Cell Biol. 2010. PMID: 20921139 Free PMC article.
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy.
Strappazzon F, Vietri-Rudan M, Campello S, Nazio F, Florenzano F, Fimia GM, Piacentini M, Levine B, Cecconi F. Strappazzon F, et al. Among authors: fimia gm. EMBO J. 2011 Apr 6;30(7):1195-208. doi: 10.1038/emboj.2011.49. Epub 2011 Feb 25. EMBO J. 2011. PMID: 21358617 Free PMC article.
173 results