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Emerging tools to investigate bromodomain functions.
Kougnassoukou Tchara PE, Filippakopoulos P, Lambert JP. Kougnassoukou Tchara PE, et al. Among authors: filippakopoulos p. Methods. 2020 Dec 1;184:40-52. doi: 10.1016/j.ymeth.2019.11.003. Epub 2019 Nov 11. Methods. 2020. PMID: 31726225 Review.
Bromodomains as therapeutic targets.
Muller S, Filippakopoulos P, Knapp S. Muller S, et al. Among authors: filippakopoulos p. Expert Rev Mol Med. 2011 Sep 13;13:e29. doi: 10.1017/S1462399411001992. Expert Rev Mol Med. 2011. PMID: 21933453 Free PMC article. Review.
The bromodomain interaction module.
Filippakopoulos P, Knapp S. Filippakopoulos P, et al. FEBS Lett. 2012 Aug 14;586(17):2692-704. doi: 10.1016/j.febslet.2012.04.045. Epub 2012 May 3. FEBS Lett. 2012. PMID: 22710155 Free article. Review.
Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.
Picaud S, Leonards K, Lambert JP, Dovey O, Wells C, Fedorov O, Monteiro O, Fujisawa T, Wang CY, Lingard H, Tallant C, Nikbin N, Guetzoyan L, Ingham R, Ley SV, Brennan P, Muller S, Samsonova A, Gingras AC, Schwaller J, Vassiliou G, Knapp S, Filippakopoulos P. Picaud S, et al. Among authors: filippakopoulos p. Sci Adv. 2016 Oct 12;2(10):e1600760. doi: 10.1126/sciadv.1600760. eCollection 2016 Oct. Sci Adv. 2016. PMID: 27757418 Free PMC article.
Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.
Savitsky P, Krojer T, Fujisawa T, Lambert JP, Picaud S, Wang CY, Shanle EK, Krajewski K, Friedrichsen H, Kanapin A, Goding C, Schapira M, Samsonova A, Strahl BD, Gingras AC, Filippakopoulos P. Savitsky P, et al. Among authors: filippakopoulos p. Cell Rep. 2016 Dec 6;17(10):2724-2737. doi: 10.1016/j.celrep.2016.11.014. Cell Rep. 2016. PMID: 27926874 Free PMC article.
96 results