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Structural investigation of the C-terminal catalytic fragment of presenilin 1.
Sobhanifar S, Schneider B, Löhr F, Gottstein D, Ikeya T, Mlynarczyk K, Pulawski W, Ghoshdastider U, Kolinski M, Filipek S, Güntert P, Bernhard F, Dötsch V. Sobhanifar S, et al. Among authors: filipek s. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9644-9. doi: 10.1073/pnas.1000778107. Epub 2010 May 5. Proc Natl Acad Sci U S A. 2010. PMID: 20445084 Free PMC article.
Amyloid β-peptide 25-35 self-assembly and its inhibition: a model undecapeptide system to gain atomistic and secondary structure details of the Alzheimer's disease process and treatment.
Naldi M, Fiori J, Pistolozzi M, Drake AF, Bertucci C, Wu R, Mlynarczyk K, Filipek S, De Simone A, Andrisano V. Naldi M, et al. Among authors: filipek s. ACS Chem Neurosci. 2012 Nov 21;3(11):952-62. doi: 10.1021/cn3000982. Epub 2012 Sep 4. ACS Chem Neurosci. 2012. PMID: 23173074 Free PMC article.
A patient with posterior cortical atrophy possesses a novel mutation in the presenilin 1 gene.
Sitek EJ, Narożańska E, Pepłońska B, Filipek S, Barczak A, Styczyńska M, Mlynarczyk K, Brockhuis B, Portelius E, Religa D, Barcikowska M, Sławek J, Żekanowski C. Sitek EJ, et al. Among authors: filipek s. PLoS One. 2013 Apr 12;8(4):e61074. doi: 10.1371/journal.pone.0061074. Print 2013. PLoS One. 2013. PMID: 23593396 Free PMC article.
Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.
Jarmuła A, Wilk P, Maj P, Ludwiczak J, Dowierciał A, Banaszak K, Rypniewski W, Cieśla J, Dąbrowska M, Frączyk T, Bronowska AK, Jakowiecki J, Filipek S, Rode W. Jarmuła A, et al. Among authors: filipek s. J Mol Graph Model. 2017 Oct;77:33-50. doi: 10.1016/j.jmgm.2017.08.008. Epub 2017 Aug 12. J Mol Graph Model. 2017. PMID: 28826032
134 results