Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding.
Tarafder AK, Wasmeier C, Figueiredo AC, Booth AE, Orihara A, Ramalho JS, Hume AN, Seabra MC.
Tarafder AK, et al. Among authors: figueiredo ac.
Traffic. 2011 Aug;12(8):1056-66. doi: 10.1111/j.1600-0854.2011.01216.x. Epub 2011 Jun 15.
Traffic. 2011.
PMID: 21554507
Free PMC article.
Its effectors have been characterized extensively, and we have identified Rab3GEP as the non-redundant Rab27a GEF in melanocytes (Figueiredo AC et al. Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes. ...
Its effectors have been characterized extensively, and we have identified Rab3GEP as the non-redundant Rab27a GEF in melanocytes (Figueir …