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Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria.
J Med Chem. 2023 Aug 24;66(16):11294-11323. doi: 10.1021/acs.jmedchem.3c00763. Epub 2023 Aug 15.
J Med Chem. 2023.
PMID: 37582241
Free PMC article.
Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Katinas JM, Nayeen MJ, Schneider M, Shah K, Fifer AN, Klapper LM, Sharma A, Thalluri K, Van Nieuwenhze MS, Hou Z, Gangjee A, Matherly LH, Dann CE 3rd.
Katinas JM, et al. Among authors: fifer an.
Biochemistry. 2024 Feb 7. doi: 10.1021/acs.biochem.3c00613. Online ahead of print.
Biochemistry. 2024.
PMID: 38324671
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