Fields S - Search Results

1

The role of functional data in interpreting the effects of genetic variation.

Young DL, Fields S. Young DL, et al. Among authors: fields s. Mol Biol Cell. 2015 Nov 5;26(22):3904-8. doi: 10.1091/mbc.E15-03-0153. Mol Biol Cell. 2015. PMID: 26543197 Free PMC article.

2

Assigning function to yeast proteins by integration of technologies.

Hazbun TR, Malmström L, Anderson S, Graczyk BJ, Fox B, Riffle M, Sundin BA, Aranda JD, McDonald WH, Chiu CH, Snydsman BE, Bradley P, Muller EG, Fields S, Baker D, Yates JR 3rd, Davis TN. Hazbun TR, et al. Among authors: fields s. Mol Cell. 2003 Dec;12(6):1353-65. doi: 10.1016/s1097-2765(03)00476-3. Mol Cell. 2003. PMID: 14690591 Free article.

3

Wide variation in antibiotic resistance proteins identified by functional metagenomic screening of a soil DNA library.

McGarvey KM, Queitsch K, Fields S. McGarvey KM, et al. Among authors: fields s. Appl Environ Microbiol. 2012 Mar;78(6):1708-14. doi: 10.1128/AEM.06759-11. Epub 2012 Jan 13. Appl Environ Microbiol. 2012. PMID: 22247132 Free PMC article.

4

High-throughput analysis of in vivo protein stability.

Kim I, Miller CR, Young DL, Fields S. Kim I, et al. Among authors: fields s. Mol Cell Proteomics. 2013 Nov;12(11):3370-8. doi: 10.1074/mcp.O113.031708. Epub 2013 Jul 29. Mol Cell Proteomics. 2013. PMID: 23897579 Free PMC article.

5

Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly(A)-binding protein.

Melamed D, Young DL, Gamble CE, Miller CR, Fields S. Melamed D, et al. Among authors: fields s. RNA. 2013 Nov;19(11):1537-51. doi: 10.1261/rna.040709.113. Epub 2013 Sep 24. RNA. 2013. PMID: 24064791 Free PMC article.

6

Deep mutational scanning: a new style of protein science.

Fowler DM, Fields S. Fowler DM, et al. Among authors: fields s. Nat Methods. 2014 Aug;11(8):801-7. doi: 10.1038/nmeth.3027. Nat Methods. 2014. PMID: 25075907 Free PMC article.

7

Identification of the determinants of tRNA function and susceptibility to rapid tRNA decay by high-throughput in vivo analysis.

Guy MP, Young DL, Payea MJ, Zhang X, Kon Y, Dean KM, Grayhack EJ, Mathews DH, Fields S, Phizicky EM. Guy MP, et al. Among authors: fields s. Genes Dev. 2014 Aug 1;28(15):1721-32. doi: 10.1101/gad.245936.114. Genes Dev. 2014. PMID: 25085423 Free PMC article.

8

Measuring the activity of protein variants on a large scale using deep mutational scanning.

Fowler DM, Stephany JJ, Fields S. Fowler DM, et al. Among authors: fields s. Nat Protoc. 2014 Sep;9(9):2267-84. doi: 10.1038/nprot.2014.153. Epub 2014 Aug 28. Nat Protoc. 2014. PMID: 25167058 Free PMC article.

9

Combining natural sequence variation with high throughput mutational data to reveal protein interaction sites.

Melamed D, Young DL, Miller CR, Fields S. Melamed D, et al. Among authors: fields s. PLoS Genet. 2015 Feb 11;11(2):e1004918. doi: 10.1371/journal.pgen.1004918. eCollection 2015 Feb. PLoS Genet. 2015. PMID: 25671604 Free PMC article.

10

Massively Parallel Functional Analysis of BRCA1 RING Domain Variants.

Starita LM, Young DL, Islam M, Kitzman JO, Gullingsrud J, Hause RJ, Fowler DM, Parvin JD, Shendure J, Fields S. Starita LM, et al. Among authors: fields s. Genetics. 2015 Jun;200(2):413-22. doi: 10.1534/genetics.115.175802. Epub 2015 Mar 30. Genetics. 2015. PMID: 25823446 Free PMC article.

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