Fields FR - Search Results

1

Using bacterial genomes and essential genes for the development of new antibiotics.

Fields FR, Lee SW, McConnell MJ. Fields FR, et al. Biochem Pharmacol. 2017 Jun 15;134:74-86. doi: 10.1016/j.bcp.2016.12.002. Epub 2016 Dec 8. Biochem Pharmacol. 2017. PMID: 27940263 Free PMC article. Review.

2

Rational design of syn-safencin, a novel linear antimicrobial peptide derived from the circular bacteriocin safencin AS-48.

Fields FR, Carothers KE, Balsara RD, Ploplis VA, Castellino FJ, Lee SW. Fields FR, et al. J Antibiot (Tokyo). 2018 Jun;71(6):592-600. doi: 10.1038/s41429-018-0032-4. Epub 2018 Feb 20. J Antibiot (Tokyo). 2018. PMID: 29463889 Free PMC article.

3

Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains.

Fields FR, Freed SD, Carothers KE, Hamid MN, Hammers DE, Ross JN, Kalwajtys VR, Gonzalez AJ, Hildreth AD, Friedberg I, Lee SW. Fields FR, et al. Drug Dev Res. 2020 Feb;81(1):43-51. doi: 10.1002/ddr.21601. Epub 2019 Sep 4. Drug Dev Res. 2020. PMID: 31483516 Free PMC article.

4

Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy.

Fields FR, Manzo G, Hind CK, Janardhanan J, Foik IP, Carmo Silva PD, Balsara RD, Clifford M, Vu HM, Ross JN, Kalwajtys VR, Gonzalez AJ, Bui TT, Ploplis VA, Castellino FJ, Siryaporn A, Chang M, Sutton JM, Mason AJ, Lee S. Fields FR, et al. ACS Pharmacol Transl Sci. 2020 Feb 21;3(3):418-424. doi: 10.1021/acsptsci.0c00001. eCollection 2020 Jun 12. ACS Pharmacol Transl Sci. 2020. PMID: 32566907 Free PMC article.

5

Algorithmic assessment of missense mutation severity in the Von-Hippel Lindau protein.

Fields FR, Suresh N, Hiller M, Freed SD, Haldar K, Lee SW. Fields FR, et al. PLoS One. 2020 Nov 5;15(11):e0234100. doi: 10.1371/journal.pone.0234100. eCollection 2020. PLoS One. 2020. PMID: 33151962 Free PMC article.

6

Synthetic Peptide Libraries Designed From a Minimal Alpha-Helical Domain of AS-48-Bacteriocin Homologs Exhibit Potent Antibacterial Activity.

Ross JN, Fields FR, Kalwajtys VR, Gonzalez AJ, O'Connor S, Zhang A, Moran TE, Hammers DE, Carothers KE, Lee SW. Ross JN, et al. Among authors: fields fr. Front Microbiol. 2020 Nov 12;11:589666. doi: 10.3389/fmicb.2020.589666. eCollection 2020. Front Microbiol. 2020. PMID: 33281785 Free PMC article.

7

A Seed-Endophytic Bacillus safensis Strain With Antimicrobial Activity Has Genes for Novel Bacteriocin-Like Antimicrobial Peptides.

Romero-Severson J, Moran TE, Shrader DG, Fields FR, Pandey-Joshi S, Thomas CL, Palmer EC, Shrout JD, Pfrender ME, Lee SW. Romero-Severson J, et al. Among authors: fields fr. Front Microbiol. 2021 Sep 27;12:734216. doi: 10.3389/fmicb.2021.734216. eCollection 2021. Front Microbiol. 2021. PMID: 34646254 Free PMC article.

8

Rationally Designed Minimal Bioactive Domains of AS-48 Bacteriocin Homologs Possess Potent Antileishmanial Properties.

Corman HN, Ross JN, Fields FR, Shoue DA, McDowell MA, Lee SW. Corman HN, et al. Among authors: fields fr. Microbiol Spectr. 2022 Dec 21;10(6):e0265822. doi: 10.1128/spectrum.02658-22. Epub 2022 Nov 7. Microbiol Spectr. 2022. PMID: 36342284 Free PMC article.

9

Safety assessment of Streptococcus salivarius DB-B5 as a probiotic candidate for oral health.

Li X, Fields FR, Ho M, Marshall-Hudson A, Gross R, Casser ME, Naito M. Li X, et al. Among authors: fields fr. Food Chem Toxicol. 2021 Jul;153:112277. doi: 10.1016/j.fct.2021.112277. Epub 2021 May 15. Food Chem Toxicol. 2021. PMID: 34004226 Free article. Clinical Trial.

10

Complete Genome Sequence of Streptococcus salivarius DB-B5, a Novel Probiotic Candidate Isolated from the Supragingival Plaque of a Healthy Female Subject.

Fields FR, Li X, Navarre WW, Naito M. Fields FR, et al. Microbiol Resour Announc. 2020 Oct 1;9(40):e00916-20. doi: 10.1128/MRA.00916-20. Microbiol Resour Announc. 2020. PMID: 33004456 Free PMC article.

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