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142 results

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Evaluation of cell-free DNA approaches for multi-cancer early detection.
Jamshidi A, Liu MC, Klein EA, Venn O, Hubbell E, Beausang JF, Gross S, Melton C, Fields AP, Liu Q, Zhang N, Fung ET, Kurtzman KN, Amini H, Betts C, Civello D, Freese P, Calef R, Davydov K, Fayzullina S, Hou C, Jiang R, Jung B, Tang S, Demas V, Newman J, Sakarya O, Scott E, Shenoy A, Shojaee S, Steffen KK, Nicula V, Chien TC, Bagaria S, Hunkapiller N, Desai M, Dong Z, Richards DA, Yeatman TJ, Cohn AL, Thiel DD, Berry DA, Tummala MK, McIntyre K, Sekeres MA, Bryce A, Aravanis AM, Seiden MV, Swanton C. Jamshidi A, et al. Among authors: fields ap. Cancer Cell. 2022 Dec 12;40(12):1537-1549.e12. doi: 10.1016/j.ccell.2022.10.022. Epub 2022 Nov 17. Cancer Cell. 2022. PMID: 36400018 Free article.
Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer.
Jayaraman S, Wu X, Kalari KR, Tang X, Kuffel MJ, Bruinsma ES, Jalali S, Peterson KL, Correia C, Kudgus RA, Kaufmann SH, Renuse S, Ingle JN, Reid JM, Ames MM, Fields AP, Schellenberg MJ, Hawse JR, Pandey A, Goetz MP. Jayaraman S, et al. Among authors: fields ap. NPJ Breast Cancer. 2023 Dec 19;9(1):101. doi: 10.1038/s41523-023-00606-2. NPJ Breast Cancer. 2023. PMID: 38114522 Free PMC article.
Protein kinase Cι mediates immunosuppression in lung adenocarcinoma.
Yin N, Liu Y, Weems C, Shreeder B, Lou Y, Knutson KL, Murray NR, Fields AP. Yin N, et al. Among authors: fields ap. Sci Transl Med. 2022 Nov 16;14(671):eabq5931. doi: 10.1126/scitranslmed.abq5931. Epub 2022 Nov 16. Sci Transl Med. 2022. PMID: 36383684
Prkci Regulates Autophagy and Pancreatic Tumorigenesis in Mice.
Inman KS, Liu Y, Scotti Buzhardt ML, Leitges M, Krishna M, Crawford HC, Fields AP, Murray NR. Inman KS, et al. Among authors: fields ap. Cancers (Basel). 2022 Feb 4;14(3):796. doi: 10.3390/cancers14030796. Cancers (Basel). 2022. PMID: 35159064 Free PMC article.
FoxM1 insufficiency hyperactivates Ect2-RhoA-mDia1 signaling to drive cancer.
Limzerwala JF, Jeganathan KB, Kloeber JA, Davies BA, Zhang C, Sturmlechner I, Zhong J, Fierro Velasco R, Fields AP, Yuan Y, Baker DJ, Zhou D, Li H, Katzmann DJ, van Deursen JM. Limzerwala JF, et al. Among authors: fields ap. Nat Cancer. 2020 Oct;1(10):1010-1024. doi: 10.1038/s43018-020-00116-1. Epub 2020 Oct 12. Nat Cancer. 2020. PMID: 34841254 Free PMC article.
Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities.
Kenchappa RS, Liu Y, Argenziano MG, Banu MA, Mladek AC, West R, Luu A, Quiñones-Hinojosa A, Hambardzumyan D, Justilien V, Leitges M, Sarkaria JN, Sims PA, Canoll P, Murray NR, Fields AP, Rosenfeld SS. Kenchappa RS, et al. Among authors: fields ap. Cell Rep. 2021 Nov 23;37(8):110054. doi: 10.1016/j.celrep.2021.110054. Cell Rep. 2021. PMID: 34818553 Free PMC article.
Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth.
Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ. Cook DR, et al. Among authors: fields ap. Cancer Res. 2022 Jan 1;82(1):90-104. doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 4. Cancer Res. 2022. PMID: 34737214 Free PMC article.
Editorial.
Fields AP. Fields AP. Adv Biol Regul. 2021 May;80:100770. doi: 10.1016/j.jbior.2020.100770. Epub 2020 Nov 26. Adv Biol Regul. 2021. PMID: 33310395 No abstract available.
142 results