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Disruptive anti-IgE inhibitors prevent mast cell-dependent early airway response in viable atopic lung tissue.
Delgado SJ, Dehmel S, Twisterling E, Wichmann J, Jonigk D, Warnecke G, Braubach P, Fieguth HG, Wilkens L, Dahlmann F, Kaup FJ, Eggel A, Knauf S, Sewald K, Braun A. Delgado SJ, et al. Among authors: fieguth hg. J Allergy Clin Immunol. 2020 Feb;145(2):719-722.e1. doi: 10.1016/j.jaci.2019.11.002. Epub 2019 Dec 16. J Allergy Clin Immunol. 2020. PMID: 31858993 No abstract available.
Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs.
Danov O, Jiménez Delgado SM, Obernolte H, Seehase S, Dehmel S, Braubach P, Fieguth HG, Matschiner G, Fitzgerald M, Jonigk D, Knauf S, Pfennig O, Warnecke G, Wichmann J, Braun A, Sewald K. Danov O, et al. Among authors: fieguth hg. PLoS One. 2018 Nov 30;13(11):e0207767. doi: 10.1371/journal.pone.0207767. eCollection 2018. PLoS One. 2018. PMID: 30500834 Free PMC article.
Rhinovirus-induced Human Lung Tissue Responses Mimic Chronic Obstructive Pulmonary Disease and Asthma Gene Signatures.
Wronski S, Beinke S, Obernolte H, Belyaev NN, Saunders KA, Lennon MG, Schaudien D, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth HG, Wilkens L, Braun A, Hessel EM, Sewald K. Wronski S, et al. Among authors: fieguth hg. Am J Respir Cell Mol Biol. 2021 Nov;65(5):544-554. doi: 10.1165/rcmb.2020-0337OC. Am J Respir Cell Mol Biol. 2021. PMID: 34181859 Free PMC article.
FXII promotes proteolytic processing of the LRP1 ectodomain.
Wujak L, Hesse C, Sewald K, Jonigk D, Braubach P, Warnecke G, Fieguth HG, Braun A, Lochnit G, Markart P, Schaefer L, Wygrecka M. Wujak L, et al. Among authors: fieguth hg. Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):2088-2098. doi: 10.1016/j.bbagen.2017.05.023. Epub 2017 May 25. Biochim Biophys Acta Gen Subj. 2017. PMID: 28552561
Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality.
Neuhaus V, Schaudien D, Golovina T, Temann UA, Thompson C, Lippmann T, Bersch C, Pfennig O, Jonigk D, Braubach P, Fieguth HG, Warnecke G, Yusibov V, Sewald K, Braun A. Neuhaus V, et al. Among authors: fieguth hg. J Occup Med Toxicol. 2017 May 26;12:13. doi: 10.1186/s12995-017-0158-5. eCollection 2017. J Occup Med Toxicol. 2017. PMID: 28559920 Free PMC article.
104 results