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Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites.
Frame IJ, Deniskin R, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH. Frame IJ, et al. Among authors: fidock da. ACS Chem Biol. 2015 Mar 20;10(3):775-83. doi: 10.1021/cb500981y. Epub 2015 Jan 30. ACS Chem Biol. 2015. PMID: 25602169 Free PMC article.
Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE.
Nkrumah LJ, Riegelhaupt PM, Moura P, Johnson DJ, Patel J, Hayton K, Ferdig MT, Wellems TE, Akabas MH, Fidock DA. Nkrumah LJ, et al. Among authors: fidock da. Mol Biochem Parasitol. 2009 Jun;165(2):122-31. doi: 10.1016/j.molbiopara.2009.01.011. Epub 2009 Jan 30. Mol Biochem Parasitol. 2009. PMID: 19428659 Free PMC article.
Taking Charge: Feeding Malaria via Anion Channels.
Ekland EH, Akabas MH, Fidock DA. Ekland EH, et al. Among authors: fidock da. Cell. 2011 May 27;145(5):645-7. doi: 10.1016/j.cell.2011.05.012. Cell. 2011. PMID: 21620131 Free article.
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue.
Adjalley SH, Johnston GL, Li T, Eastman RT, Ekland EH, Eappen AG, Richman A, Sim BK, Lee MC, Hoffman SL, Fidock DA. Adjalley SH, et al. Among authors: fidock da. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):E1214-23. doi: 10.1073/pnas.1112037108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042867 Free PMC article.
UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.
Brunner R, Ng CL, Aissaoui H, Akabas MH, Boss C, Brun R, Callaghan PS, Corminboeuf O, Fidock DA, Frame IJ, Heidmann B, Le Bihan A, Jenö P, Mattheis C, Moes S, Müller IB, Paguio M, Roepe PD, Siegrist R, Voss T, Welford RW, Wittlin S, Binkert C. Brunner R, et al. Among authors: fidock da. J Biol Chem. 2013 Aug 2;288(31):22576-83. doi: 10.1074/jbc.M113.453159. Epub 2013 Jun 10. J Biol Chem. 2013. PMID: 23754276 Free PMC article.
288 results