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Stephalagine, an aporphine alkaloid from Annona crassiflora fruit peel, induces antinociceptive effects by TRPA1 and TRPV1 channels modulation in mice.
Justino AB, Barbosa MF, Neves TV, Silva HCG, Brum EDS, Fialho MFP, Couto AC, Saraiva AL, Avila VMR, Oliveira SM, Pivatto M, Espindola FS, Silva CR. Justino AB, et al. Among authors: fialho mfp. Bioorg Chem. 2020 Mar;96:103562. doi: 10.1016/j.bioorg.2019.103562. Epub 2020 Jan 16. Bioorg Chem. 2020. PMID: 31981911
TRPA1 activation mediates nociception behaviors in a mouse model of relapsing-remitting experimental autoimmune encephalomyelitis.
Dalenogare DP, Theisen MC, Peres DS, Fialho MFP, Lückemeyer DD, Antoniazzi CTD, Kudsi SQ, Ferreira MA, Ritter CDS, Ferreira J, Oliveira SM, Trevisan G. Dalenogare DP, et al. Among authors: fialho mfp. Exp Neurol. 2020 Jun;328:113241. doi: 10.1016/j.expneurol.2020.113241. Epub 2020 Feb 8. Exp Neurol. 2020. PMID: 32045597 Free article.
Animal models of fibromyalgia: What is the best choice?
Brum ES, Becker G, Fialho MFP, Oliveira SM. Brum ES, et al. Among authors: fialho mfp. Pharmacol Ther. 2022 Feb;230:107959. doi: 10.1016/j.pharmthera.2021.107959. Epub 2021 Jul 12. Pharmacol Ther. 2022. PMID: 34265360 Review.
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