Fex M - Search Results

1

A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells.

Ye Y, Barghouth M, Dou H, Luan C, Wang Y, Karagiannopoulos A, Jiang X, Krus U, Fex M, Zhang Q, Eliasson L, Rorsman P, Zhang E, Renström E. Ye Y, et al. Among authors: fex m. Nat Commun. 2022 Jul 22;13(1):4237. doi: 10.1038/s41467-022-31103-y. Nat Commun. 2022. PMID: 35869052 Free PMC article.

2

Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact.

Fex M, Olofsson CS, Fransson U, Bacos K, Lindvall H, Sörhede-Winzell M, Rorsman P, Holm C, Mulder H. Fex M, et al. Endocrinology. 2004 Aug;145(8):3746-53. doi: 10.1210/en.2003-1673. Epub 2004 May 13. Endocrinology. 2004. PMID: 15142983

3

The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient beta-cell mass and exocytosis.

Björkqvist M, Fex M, Renström E, Wierup N, Petersén A, Gil J, Bacos K, Popovic N, Li JY, Sundler F, Brundin P, Mulder H. Björkqvist M, et al. Among authors: fex m. Hum Mol Genet. 2005 Mar 1;14(5):565-74. doi: 10.1093/hmg/ddi053. Epub 2005 Jan 13. Hum Mol Genet. 2005. PMID: 15649949

4

Lipases in the pancreatic beta-cell: implications for insulin secretion.

Fex M, Mulder H. Fex M, et al. Biochem Soc Trans. 2008 Oct;36(Pt 5):885-90. doi: 10.1042/BST0360885. Biochem Soc Trans. 2008. PMID: 18793156 Review.

5

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis.

Fex M, Haemmerle G, Wierup N, Dekker-Nitert M, Rehn M, Ristow M, Zechner R, Sundler F, Holm C, Eliasson L, Mulder H. Fex M, et al. Diabetologia. 2009 Feb;52(2):271-80. doi: 10.1007/s00125-008-1191-9. Epub 2008 Nov 21. Diabetologia. 2009. PMID: 19023560

6

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.

Lyssenko V, Nagorny CL, Erdos MR, Wierup N, Jonsson A, Spégel P, Bugliani M, Saxena R, Fex M, Pulizzi N, Isomaa B, Tuomi T, Nilsson P, Kuusisto J, Tuomilehto J, Boehnke M, Altshuler D, Sundler F, Eriksson JG, Jackson AU, Laakso M, Marchetti P, Watanabe RM, Mulder H, Groop L. Lyssenko V, et al. Among authors: fex m. Nat Genet. 2009 Jan;41(1):82-8. doi: 10.1038/ng.288. Epub 2008 Dec 7. Nat Genet. 2009. PMID: 19060908 Free PMC article.

7

The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events.

Krus U, King BC, Nagaraj V, Gandasi NR, Sjölander J, Buda P, Garcia-Vaz E, Gomez MF, Ottosson-Laakso E, Storm P, Fex M, Vikman P, Zhang E, Barg S, Blom AM, Renström E. Krus U, et al. Among authors: fex m. Cell Metab. 2014 May 6;19(5):883-90. doi: 10.1016/j.cmet.2014.03.001. Epub 2014 Apr 10. Cell Metab. 2014. PMID: 24726385 Free article.

8

TCF7L2 is a master regulator of insulin production and processing.

Zhou Y, Park SY, Su J, Bailey K, Ottosson-Laakso E, Shcherbina L, Oskolkov N, Zhang E, Thevenin T, Fadista J, Bennet H, Vikman P, Wierup N, Fex M, Rung J, Wollheim C, Nobrega M, Renström E, Groop L, Hansson O. Zhou Y, et al. Among authors: fex m. Hum Mol Genet. 2014 Dec 15;23(24):6419-31. doi: 10.1093/hmg/ddu359. Epub 2014 Jul 11. Hum Mol Genet. 2014. PMID: 25015099 Free PMC article.

9

Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes.

Bennet H, Balhuizen A, Medina A, Dekker Nitert M, Ottosson Laakso E, Essén S, Spégel P, Storm P, Krus U, Wierup N, Fex M. Bennet H, et al. Among authors: fex m. Peptides. 2015 Sep;71:113-20. doi: 10.1016/j.peptides.2015.07.008. Epub 2015 Jul 20. Peptides. 2015. PMID: 26206285

10

Islet-specific monoamine oxidase A and B expression depends on MafA transcriptional activity and is compromised in type 2 diabetes.

Ganic E, Johansson JK, Bennet H, Fex M, Artner I. Ganic E, et al. Among authors: fex m. Biochem Biophys Res Commun. 2015 Dec 25;468(4):629-35. doi: 10.1016/j.bbrc.2015.11.002. Epub 2015 Nov 10. Biochem Biophys Res Commun. 2015. PMID: 26546820

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