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CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.
Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N. Abels M, et al. Among authors: fex m. Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23. Diabetologia. 2016. PMID: 27338624
Characterization of resident lymphocytes in human pancreatic islets.
Radenkovic M, Uvebrant K, Skog O, Sarmiento L, Avartsson J, Storm P, Vickman P, Bertilsson PA, Fex M, Korgsgren O, Cilio CM. Radenkovic M, et al. Among authors: fex m. Clin Exp Immunol. 2017 Mar;187(3):418-427. doi: 10.1111/cei.12892. Epub 2016 Dec 12. Clin Exp Immunol. 2017. PMID: 27783386 Free PMC article.
Glycogen metabolism in the glucose-sensing and supply-driven β-cell.
Andersson LE, Nicholas LM, Filipsson K, Sun J, Medina A, Al-Majdoub M, Fex M, Mulder H, Spégel P. Andersson LE, et al. Among authors: fex m. FEBS Lett. 2016 Dec;590(23):4242-4251. doi: 10.1002/1873-3468.12460. Epub 2016 Nov 5. FEBS Lett. 2016. PMID: 27943300 Free article.
Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats.
Medina A, Parween S, Ullsten S, Vishnu N, Siu YT, Quach M, Bennet H, Balhuizen A, Åkesson L, Wierup N, Carlsson PO, Ahlgren U, Lernmark Å, Fex M. Medina A, et al. Among authors: fex m. Diabetologia. 2018 Apr;61(4):896-905. doi: 10.1007/s00125-017-4512-z. Epub 2017 Dec 6. Diabetologia. 2018. PMID: 29209740 Free PMC article.
68 results