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GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.
Heitzeneder S, Bosse KR, Zhu Z, Zhelev D, Majzner RG, Radosevich MT, Dhingra S, Sotillo E, Buongervino S, Pascual-Pasto G, Garrigan E, Xu P, Huang J, Salzer B, Delaidelli A, Raman S, Cui H, Martinez B, Bornheimer SJ, Sahaf B, Alag A, Fetahu IS, Hasselblatt M, Parker KR, Anbunathan H, Hwang J, Huang M, Sakamoto K, Lacayo NJ, Klysz DD, Theruvath J, Vilches-Moure JG, Satpathy AT, Chang HY, Lehner M, Taschner-Mandl S, Julien JP, Sorensen PH, Dimitrov DS, Maris JM, Mackall CL. Heitzeneder S, et al. Among authors: fetahu is. Cancer Cell. 2022 Jan 10;40(1):53-69.e9. doi: 10.1016/j.ccell.2021.12.005. Epub 2021 Dec 30. Cancer Cell. 2022. PMID: 34971569 Free PMC article.
Neuroblastoma and the epigenome.
Fetahu IS, Taschner-Mandl S. Fetahu IS, et al. Cancer Metastasis Rev. 2021 Mar;40(1):173-189. doi: 10.1007/s10555-020-09946-y. Epub 2021 Jan 6. Cancer Metastasis Rev. 2021. PMID: 33404859 Free PMC article. Review.
Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis.
Fetahu IS, Esser-Skala W, Dnyansagar R, Sindelar S, Rifatbegovic F, Bileck A, Skos L, Bozsaky E, Lazic D, Shaw L, Tötzl M, Tarlungeanu D, Bernkopf M, Rados M, Weninger W, Tomazou EM, Bock C, Gerner C, Ladenstein R, Farlik M, Fortelny N, Taschner-Mandl S. Fetahu IS, et al. Nat Commun. 2023 Jun 26;14(1):3620. doi: 10.1038/s41467-023-39210-0. Nat Commun. 2023. PMID: 37365178 Free PMC article.
Calcium sensing receptor signalling in physiology and cancer.
Brennan SC, Thiem U, Roth S, Aggarwal A, Fetahu ISh, Tennakoon S, Gomes AR, Brandi ML, Bruggeman F, Mentaverri R, Riccardi D, Kallay E. Brennan SC, et al. Biochim Biophys Acta. 2013 Jul;1833(7):1732-44. doi: 10.1016/j.bbamcr.2012.12.011. Epub 2012 Dec 23. Biochim Biophys Acta. 2013. PMID: 23267858 Free article. Review.
16 results