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PDE4-Mediated cAMP Signalling.
Fertig BA, Baillie GS. Fertig BA, et al. J Cardiovasc Dev Dis. 2018 Jan 31;5(1):8. doi: 10.3390/jcdd5010008. J Cardiovasc Dev Dis. 2018. PMID: 29385021 Free PMC article. Review.
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar F, Findlay JE, Carfray G, Allcock RW, Jiang Z, Moore C, Muir AL, Lannoy M, Fertig BA, Mai D, Day JP, Bolger G, Baillie GS, Schwiebert E, Klussmann E, Pyne NJ, Ong ACM, Bowers K, Adam JM, Adams DR, Houslay MD, Henderson DJP. Omar F, et al. Among authors: fertig ba. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13320-13329. doi: 10.1073/pnas.1822113116. Epub 2019 Jun 17. Proc Natl Acad Sci U S A. 2019. PMID: 31209056 Free PMC article.
SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca2.
Fertig B, Ling J, Nollet EE, Dobi S, Busiau T, Ishikawa K, Yamada K, Lee A, Kho C, Wills L, Tibbo AJ, Scott M, Grant K, Campbell KS, Birks EJ, MacQuaide N, Hajjar R, Smith GL, van der Velden J, Baillie GS. Fertig B, et al. FEBS J. 2022 Oct;289(20):6267-6285. doi: 10.1111/febs.16537. Epub 2022 Jun 8. FEBS J. 2022. PMID: 35633070 Free PMC article.