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A Diverse View of Science to Catalyse Change.
Urbina-Blanco CA, Jilani SZ, Speight IR, Bojdys MJ, Friščić T, Stoddart JF, Nelson TL, Mack J, Robinson RAS, Waddell EA, Lutkenhaus JL, Godfrey M, Abboud MI, Aderinto SO, Aderohunmu D, Bibič L, Borges J, Dong VM, Ferrins L, Fung FM, John T, Lim FPL, Masters SL, Mambwe D, Thordarson P, Titirici MM, Tormet-González GD, Unterlass MM, Wadle A, Yam VW, Yang YW. Urbina-Blanco CA, et al. Among authors: ferrins l. Angew Chem Int Ed Engl. 2020 Oct 12;59(42):18306-18310. doi: 10.1002/anie.202009834. Epub 2020 Aug 17. Angew Chem Int Ed Engl. 2020. PMID: 33448562 Free PMC article. Review.
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.
Jansen J, Reimer KC, Nagai JS, Varghese FS, Overheul GJ, de Beer M, Roverts R, Daviran D, Fermin LAS, Willemsen B, Beukenboom M, Djudjaj S, von Stillfried S, van Eijk LE, Mastik M, Bulthuis M, Dunnen WD, van Goor H, Hillebrands JL, Triana SH, Alexandrov T, Timm MC, van den Berge BT, van den Broek M, Nlandu Q, Heijnert J, Bindels EMJ, Hoogenboezem RM, Mooren F, Kuppe C, Miesen P, Grünberg K, Ijzermans T, Steenbergen EJ, Czogalla J, Schreuder MF, Sommerdijk N, Akiva A, Boor P, Puelles VG, Floege J, Huber TB; COVID Moonshot consortium; van Rij RP, Costa IG, Schneider RK, Smeets B, Kramann R. Jansen J, et al. Cell Stem Cell. 2022 Feb 3;29(2):217-231.e8. doi: 10.1016/j.stem.2021.12.010. Epub 2021 Dec 25. Cell Stem Cell. 2022. PMID: 35032430 Free PMC article.
Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes.
Ferrins L, Buskes MJ, Kapteyn MM, Engels HN, Enos SE, Lu C, Klug DM, Singh B, Quotadamo A, Bachovchin K, Tear WF, Spaulding AE, Forbes KC, Bag S, Rivers M, LeBlanc C, Burchfield E, Armand JR, Diaz-Gonzalez R, Ceballos-Perez G, García-Hernández R, Pérez-Moreno G, Bosch-Navarrete C, Ruiz-Pérez LM, Gamarro F, González-Pacanowska D, Navarro M, Mensa-Wilmot K, Pollastri MP, Kyle DE, Rice CA. Ferrins L, et al. Front Microbiol. 2023 May 10;14:1149145. doi: 10.3389/fmicb.2023.1149145. eCollection 2023. Front Microbiol. 2023. PMID: 37234530 Free PMC article.
Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2.
Sanders BC, Pokhrel S, Labbe AD, Mathews II, Cooper CJ, Davidson RB, Phillips G, Weiss KL, Zhang Q, O'Neill H, Kaur M, Schmidt JG, Reichard W, Surendranathan S, Parvathareddy J, Phillips L, Rainville C, Sterner DE, Kumaran D, Andi B, Babnigg G, Moriarty NW, Adams PD, Joachimiak A, Hurst BL, Kumar S, Butt TR, Jonsson CB, Ferrins L, Wakatsuki S, Galanie S, Head MS, Parks JM. Sanders BC, et al. Among authors: ferrins l. Nat Commun. 2023 Mar 28;14(1):1733. doi: 10.1038/s41467-023-37254-w. Nat Commun. 2023. PMID: 36977673 Free PMC article.
A Diverse View of Science to Catalyse Change.
Urbina-Blanco CA, Jilani SZ, Speight IR, Bojdys MJ, Friščić T, Stoddart JF, Nelson TL, Mack J, Robinson RAS, Waddell EA, Lutkenhaus JL, Godfrey M, Abboud MI, Aderinto SO, Aderohunmu D, Bibič L, Borges J, Dong VM, Ferrins L, Fung FM, John T, Lim FPL, Masters SL, Mambwe D, Thordarson P, Titirici MM, Tormet-González GD, Unterlass MM, Wadle A, Yam VW, Yang YW. Urbina-Blanco CA, et al. Among authors: ferrins l. J Am Chem Soc. 2020 Aug 26;142(34):14393-14396. doi: 10.1021/jacs.0c07877. Epub 2020 Aug 17. J Am Chem Soc. 2020. PMID: 32803980 No abstract available.
A diverse view of science to catalyse change.
Urbina-Blanco CA, Jilani SZ, Speight IR, Bojdys MJ, Friščić T, Stoddart JF, Nelson TL, Mack J, Robinson RAS, Waddell EA, Lutkenhaus JL, Godfrey M, Abboud MI, Aderinto SO, Aderohunmu D, Bibič L, Borges J, Dong VM, Ferrins L, Fung FM, John T, Lim FPL, Masters SL, Mambwe D, Thordarson P, Titirici MM, Tormet-González GD, Unterlass MM, Wadle A, Yam VW, Yang YW. Urbina-Blanco CA, et al. Among authors: ferrins l. Nat Chem. 2020 Sep;12(9):773-776. doi: 10.1038/s41557-020-0529-x. Nat Chem. 2020. PMID: 32807887 No abstract available.
3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.
Ferrins L, Rahmani R, Sykes ML, Jones AJ, Avery VM, Teston E, Almohaywi B, Yin J, Smith J, Hyland C, White KL, Ryan E, Campbell M, Charman SA, Kaiser M, Baell JB. Ferrins L, et al. Eur J Med Chem. 2013 Aug;66:450-65. doi: 10.1016/j.ejmech.2013.05.007. Epub 2013 May 16. Eur J Med Chem. 2013. PMID: 23831695
Improvement of Aqueous Solubility of Lapatinib-Derived Analogues: Identification of a Quinolinimine Lead for Human African Trypanosomiasis Drug Development.
Bachovchin KA, Sharma A, Bag S, Klug DM, Schneider KM, Singh B, Jalani HB, Buskes MJ, Mehta N, Tanghe S, Momper JD, Sciotti RJ, Rodriguez A, Mensa-Wilmot K, Pollastri MP, Ferrins L. Bachovchin KA, et al. Among authors: ferrins l. J Med Chem. 2019 Jan 24;62(2):665-687. doi: 10.1021/acs.jmedchem.8b01365. Epub 2019 Jan 10. J Med Chem. 2019. PMID: 30565932 Free PMC article.
40 results