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Luminal cysteine-proteases degrade colonic tight junction structure and are responsible for abdominal pain in constipation-predominant IBS.
Annaházi A, Ferrier L, Bézirard V, Lévêque M, Eutamène H, Ait-Belgnaoui A, Coëffier M, Ducrotté P, Róka R, Inczefi O, Gecse K, Rosztóczy A, Molnár T, Ringel-Kulka T, Ringel Y, Piche T, Theodorou V, Wittmann T, Bueno L. Annaházi A, et al. Among authors: ferrier l. Am J Gastroenterol. 2013 Aug;108(8):1322-31. doi: 10.1038/ajg.2013.152. Epub 2013 May 28. Am J Gastroenterol. 2013. PMID: 23711626
Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation.
Martin OCB, Olier M, Ellero-Simatos S, Naud N, Dupuy J, Huc L, Taché S, Graillot V, Levêque M, Bézirard V, Héliès-Toussaint C, Estrada FBY, Tondereau V, Lippi Y, Naylies C, Peyriga L, Canlet C, Davila AM, Blachier F, Ferrier L, Boutet-Robinet E, Guéraud F, Théodorou V, Pierre FHF. Martin OCB, et al. Among authors: ferrier l. Microbiome. 2019 May 6;7(1):72. doi: 10.1186/s40168-019-0685-7. Microbiome. 2019. PMID: 31060614 Free PMC article.
Pharmacological restoration of gut barrier function in stressed neonates partially reverses long-term alterations associated with maternal separation.
Rincel M, Olier M, Minni A, Monchaux de Oliveira C, Matime Y, Gaultier E, Grit I, Helbling JC, Costa AM, Lépinay A, Moisan MP, Layé S, Ferrier L, Parnet P, Theodorou V, Darnaudéry M. Rincel M, et al. Among authors: ferrier l. Psychopharmacology (Berl). 2019 May;236(5):1583-1596. doi: 10.1007/s00213-019-05252-w. Epub 2019 May 23. Psychopharmacology (Berl). 2019. PMID: 31147734
Stress disrupts intestinal mucus barrier in rats via mucin O-glycosylation shift: prevention by a probiotic treatment.
Da Silva S, Robbe-Masselot C, Ait-Belgnaoui A, Mancuso A, Mercade-Loubière M, Salvador-Cartier C, Gillet M, Ferrier L, Loubière P, Dague E, Theodorou V, Mercier-Bonin M. Da Silva S, et al. Among authors: ferrier l. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G420-9. doi: 10.1152/ajpgi.00290.2013. Epub 2014 Jun 26. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24970779 Free article.
Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses.
Inczefi O, Bacquié V, Olier-Pierre M, Rincel M, Ringot-Destrez B, Ellero-Simatos S, Eutamène H, Bétoulières C, Thomas J, Lainé J, Gros L, Lévêque M, Leonard R, Harkat C, Robbe-Masselot C, Róka R, Mercier-Bonin M, Theodorou V, Darnaudéry M, Turner JR, Ferrier L. Inczefi O, et al. Among authors: ferrier l. Cell Mol Gastroenterol Hepatol. 2020;10(1):206-208.e3. doi: 10.1016/j.jcmgh.2020.02.008. Epub 2020 Mar 6. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32147490 Free PMC article. No abstract available.
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