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Discovery and synthesis of HIV integrase inhibitors: development of potent and orally bioavailable N-methyl pyrimidones.
J Med Chem. 2007 Oct 4;50(20):4953-75. doi: 10.1021/jm0704705. Epub 2007 Sep 8.
J Med Chem. 2007.
PMID: 17824681
Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase.
Narjes F, Crescenzi B, Ferrara M, Habermann J, Colarusso S, Ferreira Mdel R, Stansfield I, Mackay AC, Conte I, Ercolani C, Zaramella S, Palumbi MC, Meuleman P, Leroux-Roels G, Giuliano C, Fiore F, Di Marco S, Baiocco P, Koch U, Migliaccio G, Altamura S, Laufer R, De Francesco R, Rowley M.
Narjes F, et al. Among authors: ferreira mdel r.
J Med Chem. 2011 Jan 13;54(1):289-301. doi: 10.1021/jm1013105. Epub 2010 Dec 8.
J Med Chem. 2011.
PMID: 21141896
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Discovery of pentacyclic compounds as potent inhibitors of hepatitis C virus NS5B RNA polymerase.
Habermann J, Capitò E, Ferreira Mdel R, Koch U, Narjes F.
Habermann J, et al. Among authors: ferreira mdel r.
Bioorg Med Chem Lett. 2009 Feb 1;19(3):633-8. doi: 10.1016/j.bmcl.2008.12.039. Epub 2008 Dec 13.
Bioorg Med Chem Lett. 2009.
PMID: 19109015
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An enantioselective total synthesis of (+)- and (-)-saudin. Determination of the absolute configuration.
Boeckman RK Jr, Ferreira Mdel R, Mitchell LH, Shao P.
Boeckman RK Jr, et al. Among authors: ferreira mdel r.
J Am Chem Soc. 2002 Jan 16;124(2):190-1. doi: 10.1021/ja017194i.
J Am Chem Soc. 2002.
PMID: 11782168
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β-Cell adaptation/dysfunction in an animal model of dyslipidemia and insulin resistance induced by the chronic administration of a sucrose-rich diet.
Ferreira Mdel R, Lombardo YB, Chicco A.
Ferreira Mdel R, et al.
Islets. 2010 Nov-Dec;2(6):367-73. doi: 10.4161/isl.2.6.13869. Epub 2010 Nov 1.
Islets. 2010.
PMID: 21099338
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