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Pimaradienoic acid inhibits inflammatory pain: inhibition of NF-κB activation and cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway.
Possebon MI, Mizokami SS, Carvalho TT, Zarpelon AC, Hohmann MS, Staurengo-Ferrari L, Ferraz CR, Hayashida TH, de Souza AR, Ambrosio SR, Arakawa NS, Casagrande R, Verri WA Jr. Possebon MI, et al. Among authors: ferraz cr. J Nat Prod. 2014 Nov 26;77(11):2488-96. doi: 10.1021/np500563b. Epub 2014 Nov 13. J Nat Prod. 2014. PMID: 25394199
The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2.
Maioli NA, Zarpelon AC, Mizokami SS, Calixto-Campos C, Guazelli CF, Hohmann MS, Pinho-Ribeiro FA, Carvalho TT, Manchope MF, Ferraz CR, Casagrande R, Verri WA Jr. Maioli NA, et al. Among authors: ferraz cr. Braz J Med Biol Res. 2015 Apr;48(4):321-31. doi: 10.1590/1414-431X20144187. Epub 2015 Feb 13. Braz J Med Biol Res. 2015. PMID: 25714890 Free PMC article.
Hesperidin methyl chalcone interacts with NFκB Ser276 and inhibits zymosan-induced joint pain and inflammation, and RAW 264.7 macrophage activation.
Rasquel-Oliveira FS, Manchope MF, Staurengo-Ferrari L, Ferraz CR, Saraiva-Santos T, Zaninelli TH, Fattori V, Artero NA, Badaro-Garcia S, de Freitas A, Casagrande R, Verri WA Jr. Rasquel-Oliveira FS, et al. Among authors: ferraz cr. Inflammopharmacology. 2020 Aug;28(4):979-992. doi: 10.1007/s10787-020-00686-7. Epub 2020 Feb 11. Inflammopharmacology. 2020. PMID: 32048121
42 results