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LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase.
bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563158. doi: 10.1101/2023.10.19.563158.
bioRxiv. 2023.
PMID: 37904985
Free PMC article.
Preprint.
LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
Stein BD, Ferrarone JR, Gardner EE, Chang JW, Wu D, Hollstein PE, Liang RJ, Yuan M, Chen Q, Coukos JS, Sindelar M, Ngo B, Gross SS, Shaw RJ, Zhang C, Asara JM, Moellering RE, Varmus H, Cantley LC.
Stein BD, et al. Among authors: ferrarone jr.
Cancer Discov. 2023 Apr 3;13(4):1002-1025. doi: 10.1158/2159-8290.CD-22-0805.
Cancer Discov. 2023.
PMID: 36715544
Free PMC article.
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GCN2 kinase activation by ATP-competitive kinase inhibitors.
Tang CP, Clark O, Ferrarone JR, Campos C, Lalani AS, Chodera JD, Intlekofer AM, Elemento O, Mellinghoff IK.
Tang CP, et al. Among authors: ferrarone jr.
Nat Chem Biol. 2022 Feb;18(2):207-215. doi: 10.1038/s41589-021-00947-8. Epub 2021 Dec 23.
Nat Chem Biol. 2022.
PMID: 34949839
Free PMC article.
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Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.
Unni AM, Harbourne B, Oh MH, Wild S, Ferrarone JR, Lockwood WW, Varmus H.
Unni AM, et al. Among authors: ferrarone jr.
Elife. 2018 Nov 26;7:e33718. doi: 10.7554/eLife.33718.
Elife. 2018.
PMID: 30475204
Free PMC article.
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