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GCN2 kinase activation by ATP-competitive kinase inhibitors.
Nat Chem Biol. 2022 Feb;18(2):207-215. doi: 10.1038/s41589-021-00947-8. Epub 2021 Dec 23.
Nat Chem Biol. 2022.
PMID: 34949839
Free PMC article.
Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.
Unni AM, Harbourne B, Oh MH, Wild S, Ferrarone JR, Lockwood WW, Varmus H.
Unni AM, et al. Among authors: ferrarone jr.
Elife. 2018 Nov 26;7:e33718. doi: 10.7554/eLife.33718.
Elife. 2018.
PMID: 30475204
Free PMC article.
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Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.
Johnson FD, Ferrarone J, Liu A, Brandstädter C, Munuganti R, Farnsworth DA, Lu D, Luu J, Sihota T, Jansen S, Nagelberg A, Shi R, Forcina GC, Zhang X, Cheng GSW, Spencer Miko SE, de Rappard-Yuswack G, Sorensen PH, Dixon SJ, Guha U, Becker K, Djaballah H, Somwar R, Varmus H, Morin GB, Lockwood WW.
Johnson FD, et al.
Cell Rep. 2022 Feb 8;38(6):110343. doi: 10.1016/j.celrep.2022.110343.
Cell Rep. 2022.
PMID: 35139387
Free PMC article.
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Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.
Fei DL, Zhen T, Durham B, Ferrarone J, Zhang T, Garrett L, Yoshimi A, Abdel-Wahab O, Bradley RK, Liu P, Varmus H.
Fei DL, et al.
Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10437-E10446. doi: 10.1073/pnas.1812669115. Epub 2018 Oct 15.
Proc Natl Acad Sci U S A. 2018.
PMID: 30322915
Free PMC article.
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Removal of either N-glycan site from the envelope receptor binding domain of Moloney and Friend but not AKV mouse ecotropic gammaretroviruses alters receptor usage.
Knoper RC, Ferrarone J, Yan Y, Lafont BA, Kozak CA.
Knoper RC, et al.
Virology. 2009 Sep 1;391(2):232-9. doi: 10.1016/j.virol.2009.06.015. Epub 2009 Jul 7.
Virology. 2009.
PMID: 19584017
Free PMC article.
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Second site mutation in the virus envelope expands the host range of a cytopathic variant of Moloney murine leukemia virus.
Ferrarone J, Knoper RC, Li R, Kozak CA.
Ferrarone J, et al.
Virology. 2012 Nov 10;433(1):7-11. doi: 10.1016/j.virol.2012.06.031. Epub 2012 Jul 24.
Virology. 2012.
PMID: 22835818
Free PMC article.
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LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase.
Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H.
Ferrarone JR, et al.
bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563158. doi: 10.1101/2023.10.19.563158.
bioRxiv. 2023.
PMID: 37904985
Free PMC article.
Preprint.
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LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
Stein BD, Ferrarone JR, Gardner EE, Chang JW, Wu D, Hollstein PE, Liang RJ, Yuan M, Chen Q, Coukos JS, Sindelar M, Ngo B, Gross SS, Shaw RJ, Zhang C, Asara JM, Moellering RE, Varmus H, Cantley LC.
Stein BD, et al. Among authors: ferrarone jr.
Cancer Discov. 2023 Apr 3;13(4):1002-1025. doi: 10.1158/2159-8290.CD-22-0805.
Cancer Discov. 2023.
PMID: 36715544
Free PMC article.
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