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The HSC niche concept has turned 31. Has our knowledge matured?
Lymperi S, Ferraro F, Scadden DT. Lymperi S, et al. Among authors: ferraro f. Ann N Y Acad Sci. 2010 Mar;1192:12-8. doi: 10.1111/j.1749-6632.2009.05223.x. Ann N Y Acad Sci. 2010. PMID: 20392212 Free PMC article. Review.
Adult stem cels and their niches.
Ferraro F, Celso CL, Scadden D. Ferraro F, et al. Adv Exp Med Biol. 2010;695:155-68. doi: 10.1007/978-1-4419-7037-4_11. Adv Exp Med Biol. 2010. PMID: 21222205 Free PMC article.
Diabetes impairs hematopoietic stem cell mobilization by altering niche function.
Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT. Ferraro F, et al. Sci Transl Med. 2011 Oct 12;3(104):104ra101. doi: 10.1126/scitranslmed.3002191. Sci Transl Med. 2011. PMID: 21998408 Free PMC article.
Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.
Sanchez-Aguilera A, Lee YJ, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DA. Sanchez-Aguilera A, et al. Among authors: ferraro f. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9607-12. doi: 10.1073/pnas.1102018108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606370 Free PMC article.
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Lane SW, et al. Among authors: ferraro f. Blood. 2011 Sep 8;118(10):2849-56. doi: 10.1182/blood-2011-03-345165. Epub 2011 Jul 15. Blood. 2011. PMID: 21765021 Free PMC article.
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.
Sykes SM, Lane SW, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, Ferraro F, Mercier F, Singh H, Brumme KM, Acharya SS, Scholl C, Tothova Z, Attar EC, Fröhling S, DePinho RA, Armstrong SA, Gilliland DG, Scadden DT. Sykes SM, et al. Among authors: ferraro f. Cell. 2011 Sep 2;146(5):697-708. doi: 10.1016/j.cell.2011.07.032. Cell. 2011. PMID: 21884932 Free PMC article.
Direct measurement of local oxygen concentration in the bone marrow of live animals.
Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Côté D, Vinogradov SA, Scadden DT, Lin CP. Spencer JA, et al. Among authors: ferraro f. Nature. 2014 Apr 10;508(7495):269-73. doi: 10.1038/nature13034. Epub 2014 Mar 2. Nature. 2014. PMID: 24590072 Free PMC article.
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Toro RD, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT. Saez B, et al. Among authors: ferraro f. Blood. 2014 Nov 6;124(19):2937-47. doi: 10.1182/blood-2014-08-593426. Epub 2014 Sep 8. Blood. 2014. PMID: 25202142 Free PMC article.
Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow.
Yu VW, Saez B, Cook C, Lotinun S, Pardo-Saganta A, Wang YH, Lymperi S, Ferraro F, Raaijmakers MH, Wu JY, Zhou L, Rajagopal J, Kronenberg HM, Baron R, Scadden DT. Yu VW, et al. Among authors: ferraro f. J Exp Med. 2015 May 4;212(5):759-74. doi: 10.1084/jem.20141843. Epub 2015 Apr 27. J Exp Med. 2015. PMID: 25918341 Free PMC article.
486 results