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Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles.
Saper VE, Ombrello MJ, Tremoulet AH, Montero-Martin G, Prahalad S, Canna S, Shimizu C, Deutsch G, Tan SY, Remmers EF, Monos D, Hahn T, Phadke OK, Cassidy E, Ferguson I, Mallajosyula V, Xu J, Rosa Duque JS, Chua GT, Ghosh D, Szymanski AM, Rubin D, Burns JC, Tian L, Fernandez-Vina MA, Mellins ED, Hollenbach JA; Drug Hypersensitivity Consortium; INCHARGE Consortium. Saper VE, et al. Among authors: fernandez vina ma. Ann Rheum Dis. 2022 Mar;81(3):406-415. doi: 10.1136/annrheumdis-2021-220578. Epub 2021 Nov 17. Ann Rheum Dis. 2022. PMID: 34789453 Free PMC article.
High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility.
Osoegawa K, Creary LE, Montero-Martín G, Mallempati KC, Gangavarapu S, Caillier SJ, Santaniello A, Isobe N, Hollenbach JA, Hauser SL, Oksenberg JR, Fernández-Viňa MA. Osoegawa K, et al. Front Immunol. 2021 May 25;12:644838. doi: 10.3389/fimmu.2021.644838. eCollection 2021. Front Immunol. 2021. PMID: 34211458 Free PMC article. Clinical Trial.
A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease.
Hollenbach JA, Norman PJ, Creary LE, Damotte V, Montero-Martin G, Caillier S, Anderson KM, Misra MK, Nemat-Gorgani N, Osoegawa K, Santaniello A, Renschen A, Marin WM, Dandekar R, Parham P, Tanner CM, Hauser SL, Fernandez-Viña M, Oksenberg JR. Hollenbach JA, et al. Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7419-7424. doi: 10.1073/pnas.1821778116. Epub 2019 Mar 25. Proc Natl Acad Sci U S A. 2019. PMID: 30910980 Free PMC article. Clinical Trial.
High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity.
Amorim LM, Augusto DG, Nemat-Gorgani N, Montero-Martin G, Marin WM, Shams H, Dandekar R, Caillier S, Parham P, Fernández-Viña MA, Oksenberg JR, Norman PJ, Hollenbach JA. Amorim LM, et al. Front Immunol. 2021 May 7;12:674778. doi: 10.3389/fimmu.2021.674778. eCollection 2021. Front Immunol. 2021. PMID: 34025673 Free PMC article.
HLA alleles and haplotypes observed in 263 US families.
Osoegawa K, Mallempati KC, Gangavarapu S, Oki A, Gendzekhadze K, Marino SR, Brown NK, Bettinotti MP, Weimer ET, Montero-Martín G, Creary LE, Vayntrub TA, Chang CJ, Askar M, Mack SJ, Fernández-Viña MA. Osoegawa K, et al. Hum Immunol. 2019 Sep;80(9):644-660. doi: 10.1016/j.humimm.2019.05.018. Epub 2019 Jun 27. Hum Immunol. 2019. PMID: 31256909 Free PMC article.
Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease.
Anderson KM, Augusto DG, Dandekar R, Shams H, Zhao C, Yusufali T, Montero-Martín G, Marin WM, Nemat-Gorgani N, Creary LE, Caillier S, Mofrad MRK, Parham P, Fernández-Viña M, Oksenberg JR, Norman PJ, Hollenbach JA. Anderson KM, et al. J Immunol. 2020 Sep 1;205(5):1323-1330. doi: 10.4049/jimmunol.2000144. Epub 2020 Jul 24. J Immunol. 2020. PMID: 32709660 Free PMC article.
Remarkably Low KIR and HLA Diversity in Amerindians Reveals Signatures of Strong Purifying Selection Shaping the Centromeric KIR Region.
Vargas LB, Beltrame MH, Ho B, Marin WM, Dandekar R, Montero-Martín G, Fernández-Viña MA, Hurtado AM, Hill KR, Tsuneto LT, Hutz MH, Salzano FM, Petzl-Erler ML, Hollenbach JA, Augusto DG. Vargas LB, et al. Among authors: fernandez vina ma. Mol Biol Evol. 2022 Jan 7;39(1):msab298. doi: 10.1093/molbev/msab298. Mol Biol Evol. 2022. PMID: 34633459 Free PMC article.
243 results