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Extensive Variation in the Activities of Pseudocerastes and Eristicophis Viper Venoms Suggests Divergent Envenoming Strategies Are Used for Prey Capture.
Op den Brouw B, Coimbra FCP, Bourke LA, Huynh TM, Vlecken DHW, Ghezellou P, Visser JC, Dobson JS, Fernandez-Rojo MA, Ikonomopoulou MP, Casewell NR, Ali SA, Fathinia B, Hodgson WC, Fry BG. Op den Brouw B, et al. Among authors: fernandez rojo ma. Toxins (Basel). 2021 Feb 2;13(2):112. doi: 10.3390/toxins13020112. Toxins (Basel). 2021. PMID: 33540884 Free PMC article.
Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling.
Fernández-Rojo MA, Gongora M, Fitzsimmons RL, Martel N, Martin SD, Nixon SJ, Brooks AJ, Ikonomopoulou MP, Martin S, Lo HP, Myers SA, Restall C, Ferguson C, Pilch PF, McGee SL, Anderson RL, Waters MJ, Hancock JF, Grimmond SM, Muscat GE, Parton RG. Fernández-Rojo MA, et al. Cell Rep. 2013 Jul 25;4(2):238-47. doi: 10.1016/j.celrep.2013.06.017. Epub 2013 Jul 11. Cell Rep. 2013. PMID: 23850288 Free article.
ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations.
Moral-Sanz J, Fernandez-Rojo MA, Potriquet J, Mukhopadhyay P, Brust A, Wilhelm P, Smallwood TB, Clark RJ, Fry BG, Alewood PF, Waddell N, Miles JJ, Mulvenna JP, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: fernandez rojo ma. Toxins (Basel). 2021 Feb 14;13(2):146. doi: 10.3390/toxins13020146. Toxins (Basel). 2021. PMID: 33672955 Free PMC article.
The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.
Moral-Sanz J, Fernandez-Rojo MA, Colmenarejo G, Kurdyukov S, Brust A, Ragnarsson L, Andersson Å, Vila SF, Cabezas-Sainz P, Wilhelm P, Vela-Sebastián A, Fernández-Carrasco I, Chin YKY, López-Mancheño Y, Smallwood TB, Clark RJ, Fry BG, King GF, Ramm GA, Alewood PF, Lewis RJ, Mulvenna JP, Boyle GM, Sanchez LE, Neely GG, Miles JJ, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: fernandez rojo ma. Br J Pharmacol. 2022 Oct;179(20):4878-4896. doi: 10.1111/bph.15923. Epub 2022 Jul 29. Br J Pharmacol. 2022. PMID: 35818835 Free article.
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation.
Fernandez-Rojo MA, Pearen MA, Burgess AG, Ikonomopoulou MP, Hoang-Le D, Genz B, Saggiomo SL, Nawaratna SSK, Poli M, Reissmann R, Gobert GN, Deutsch U, Engelhardt B, Brooks AJ, Jones A, Arosio P, Ramm GA. Fernandez-Rojo MA, et al. Sci Signal. 2024 Apr 2;17(830):eade4335. doi: 10.1126/scisignal.ade4335. Epub 2024 Apr 2. Sci Signal. 2024. PMID: 38564492
37 results