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Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence.
Coombes RC, Page K, Salari R, Hastings RK, Armstrong A, Ahmed S, Ali S, Cleator S, Kenny L, Stebbing J, Rutherford M, Sethi H, Boydell A, Swenerton R, Fernandez-Garcia D, Gleason KLT, Goddard K, Guttery DS, Assaf ZJ, Wu HT, Natarajan P, Moore DA, Primrose L, Dashner S, Tin AS, Balcioglu M, Srinivasan R, Shchegrova SV, Olson A, Hafez D, Billings P, Aleshin A, Rehman F, Toghill BJ, Hills A, Louie MC, Lin CJ, Zimmermann BG, Shaw JA. Coombes RC, et al. Clin Cancer Res. 2019 Jul 15;25(14):4255-4263. doi: 10.1158/1078-0432.CCR-18-3663. Epub 2019 Apr 16. Clin Cancer Res. 2019. PMID: 30992300
The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer.
Magnani L, Patten DK, Nguyen VT, Hong SP, Steel JH, Patel N, Lombardo Y, Faronato M, Gomes AR, Woodley L, Page K, Guttery D, Primrose L, Fernandez Garcia D, Shaw J, Viola P, Green A, Nolan C, Ellis IO, Rakha EA, Shousha S, Lam EW, Győrffy B, Lupien M, Coombes RC. Magnani L, et al. Oncotarget. 2015 Sep 8;6(26):21878-91. doi: 10.18632/oncotarget.4243. Oncotarget. 2015. PMID: 26215677 Free PMC article.
Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts.
Shaw JA, Guttery DS, Hills A, Fernandez-Garcia D, Page K, Rosales BM, Goddard KS, Hastings RK, Luo J, Ogle O, Woodley L, Ali S, Stebbing J, Coombes RC. Shaw JA, et al. Clin Cancer Res. 2017 Jan 1;23(1):88-96. doi: 10.1158/1078-0432.CCR-16-0825. Epub 2016 Jun 22. Clin Cancer Res. 2017. PMID: 27334837 Free PMC article.
A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation.
Kalofonou M, Malpartida-Cardenas K, Alexandrou G, Rodriguez-Manzano J, Yu LS, Miscourides N, Allsopp R, Gleason KLT, Goddard K, Fernandez-Garcia D, Page K, Georgiou P, Ali S, Coombes RC, Shaw J, Toumazou C. Kalofonou M, et al. Sci Rep. 2020 Mar 12;10(1):4553. doi: 10.1038/s41598-020-60852-3. Sci Rep. 2020. PMID: 32165708 Free PMC article.
Longitudinal whole-exome sequencing of cell-free DNA for tracking the co-evolutionary tumor and immune evasion dynamics: longitudinal data from a single patient.
Hastings RK, Openshaw MR, Vazquez M, Moreno-Cardenas AB, Fernandez-Garcia D, Martinson L, Kulbicki K, Primrose L, Guttery DS, Page K, Toghill B, Richards C, Thomas A, Tabernero J, Coombes RC, Ahmed S, Toledo RA, Shaw JA. Hastings RK, et al. Ann Oncol. 2021 May;32(5):681-684. doi: 10.1016/j.annonc.2021.02.007. Epub 2021 Feb 18. Ann Oncol. 2021. PMID: 33609721 Free article. No abstract available.
92 results