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Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment.
Lechner L, Opitz R, Silver MJ, Krabusch PM, Prentice AM, Field MS, Stachelscheid H, Leitão E, Schröder C, Fernandez Vallone V, Horsthemke B, Jöckel KH, Schmidt B, Nöthen MM, Hoffmann P, Herms S, Kleyn PW, Megges M, Blume-Peytavi U, Weiss K, Mai K, Blankenstein O, Obermayer B, Wiegand S, Kühnen P. Lechner L, et al. Among authors: fernandez vallone v. Sci Transl Med. 2023 Jul 19;15(705):eadg1659. doi: 10.1126/scitranslmed.adg1659. Epub 2023 Jul 19. Sci Transl Med. 2023. PMID: 37467315
Generation of an NCS1 gene knockout human induced pluripotent stem cell line using CRISPR/Cas9.
Maierhof SK, Schinke C, Cernoch J, Hew L, Bruske LP, Fernandez Vallone V, Fischer K, Stachelscheid H, Huehnchen P, Endres M, Diecke S, Telugu NS, Boehmerle W. Maierhof SK, et al. Among authors: fernandez vallone v. Stem Cell Res. 2023 Dec;73:103253. doi: 10.1016/j.scr.2023.103253. Epub 2023 Nov 14. Stem Cell Res. 2023. PMID: 37984032 Free article.
Dataset for: Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC)-derived sensory neurons.
Schinke C, Fernandez Vallone V, Ivanov A, Peng Y, Körtvelyessy P, Nolte L, Huehnchen P, Beule D, Stachelscheid H, Boehmerle W, Endres M. Schinke C, et al. Among authors: fernandez vallone v. Data Brief. 2021 Aug 23;38:107320. doi: 10.1016/j.dib.2021.107320. eCollection 2021 Oct. Data Brief. 2021. PMID: 34485650 Free PMC article.
A novel approach for studying mast cell-driven disorders: Mast cells derived from induced pluripotent stem cells.
Luo Y, Fernandez Vallone V, He J, Frischbutter S, Kolkhir P, Moñino-Romero S, Stachelscheid H, Streu-Haddad V, Maurer M, Siebenhaar F, Scheffel J. Luo Y, et al. Among authors: fernandez vallone v. J Allergy Clin Immunol. 2022 Mar;149(3):1060-1068.e4. doi: 10.1016/j.jaci.2021.07.027. Epub 2021 Aug 8. J Allergy Clin Immunol. 2022. PMID: 34371081
Generation of 20 human induced pluripotent stem cell lines from patients with focal segmental glomerulosclerosis (FSGS).
Cernoch J, Fisch T, Fischer I, Fischer K, Iwanska A, Krüger N, Küchler J, Schaar C, Schommer S, Telugu N, Miller D, Fernández Vallone V, Kurtz A, Reinke P, Diecke S, Stachelscheid H. Cernoch J, et al. Among authors: fernandez vallone v. Stem Cell Res. 2021 Jul;54:102406. doi: 10.1016/j.scr.2021.102406. Epub 2021 May 25. Stem Cell Res. 2021. PMID: 34062331 Free article.
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